In search of the optimal delivery method for anti-HIV microbicides: are intravaginal rings the way forward?

Por Derby, Nina, Zydowsky, Thomas, Robbiani, Melissa
Publicado no Expert Rev Anti Infect Ther (2013)

Validation of a dye stain assay for vaginally inserted HEC-filled microbicide applicators

Por Katzen, Lauren L., Fernández-Romero, José A., Sarna, Avina, Murugavel, Kailapuri G., Gawarecki, Daniel, Zydowsky, Thomas M., Mensch, Barbara S.
Publicado em 2011

Multipurpose prevention technologies: the future of HIV and STI protection

Por Fernández-Romero, José A., Deal, Carolyn, Herold, Betsy C., Schiller, John, Patton, Dorothy, Zydowsky, Thomas, Romano, Joe, Petro, Christopher D., Narasimhan, Manjulaa
Publicado no Trends Microbiol (2015)

A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

Por Arrode-Brusés, Géraldine, Goode, Diana, Kleinbeck, Kyle, Wilk, Jolanta, Frank, Ines, Byrareddy, Siddappa, Arthos, James, Grasperge, Brooke, Blanchard, James, Zydowsky, Thomas, Gettie, Agegnehu, Martinelli, Elena
Publicado no PLoS Pathog (2016)

Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

Por Arrode-Brusés, Géraldine, Goode, Diana, Kleinbeck, Kyle, Wilk, Jolanta, Frank, Ines, Byrareddy, Siddappa, Arthos, James, Grasperge, Brooke, Blanchard, James, Zydowsky, Thomas, Gettie, Agegnehu, Martinelli, Elena
Publicado no PLoS Pathog (2016)

Short Communication: A Repeated Simian Human Immunodeficiency Virus Reverse Transcriptase/Herpes Simplex Virus Type 2 Cochallenge Macaque Model for the Evaluation of Microbicides

Por Kenney, Jessica, Derby, Nina, Aravantinou, Meropi, Kleinbeck, Kyle, Frank, Ines, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Zydowsky, Thomas M., Robbiani, Melissa
Publicado em 2014

MIV-150/Zinc Acetate Gel Inhibits Cell-Associated Simian-Human Immunodeficiency Virus Reverse Transcriptase Infection in a Macaque Vaginal Explant Model

Por Barnable, Patrick, Calenda, Giulia, Bonnaire, Thierry, Menon, Radhika, Levendosky, Keith, Gettie, Agegnehu, Blanchard, James, Cooney, Michael L., Fernández-Romero, José A., Zydowsky, Thomas M., Teleshova, Natalia
Publicado no Antimicrob Agents Chemother (2015)

MZC gel inhibits SHIV-RT and HSV-2 in macaque vaginal mucosa and SHIV-RT in rectal mucosa

Por Calenda, Giulia, Villegas, Guillermo, Barnable, Patrick, Litterst, Claudia, Levendosky, Keith, Gettie, Agegnehu, Cooney, Michael L., Blanchard, James, Fernández-Romero, José A., Zydowsky, Thomas M., Teleshova, Natalia
Publicado no J Acquir Immune Defic Syndr (2017)

Identification of Personal Lubricants That Can Cause Rectal Epithelial Cell Damage and Enhance HIV Type 1 Replication in Vitro

Por Begay, Othell, Jean-Pierre, Ninochka, Abraham, Ciby J., Chudolij, Anne, Seidor, Samantha, Rodriguez, Aixa, Ford, Brian E., Henderson, Marcus, Katz, David, Zydowsky, Thomas, Robbiani, Melissa, Fernández-Romero, José A.
Publicado em 2011

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Por Levendosky, Keith, Mizenina, Olga, Martinelli, Elena, Jean-Pierre, Ninochka, Kizima, Larisa, Rodriguez, Aixa, Kleinbeck, Kyle, Bonnaire, Thierry, Robbiani, Melissa, Zydowsky, Thomas M., O'Keefe, Barry R., Fernández-Romero, José A.
Publicado no Antimicrob Agents Chemother (2015)

A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo

Por Villegas, Guillermo, Calenda, Giulia, Ugaonkar, Shweta, Zhang, Shimin, Kizima, Larisa, Mizenina, Olga, Gettie, Agegnehu, Blanchard, James, Cooney, Michael L., Robbiani, Melissa, Fernández-Romero, José A., Zydowsky, Thomas M., Teleshova, Natalia
Publicado no PLoS One (2016)

In Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical Mucosa

Por Villegas, Guillermo, Calenda, Giulia, Zhang, Shimin, Mizenina, Olga, Kleinbeck, Kyle, Cooney, Michael L., Hoesley, Craig J., Creasy, George W., Friedland, Barbara, Fernández-Romero, José A., Zydowsky, Thomas M., Teleshova, Natalia
Publicado no Antimicrob Agents Chemother (2016)

Multipurpose Prevention Approaches with Antiretroviral-Based Formulations

Por Jean-Pierre, Ninochka, Barnable, Patrick, Kizima, Larisa, Rodríguez, Aixa, Seidor, Samantha, Cooney, Michael L., Clark, Meredith R., Doncel, Gustavo F., Robbiani, Melissa, Zydowsky, Thomas M., Teleshova, Natalia, Fernández-Romero, José A.
Publicado no Antimicrob Agents Chemother (2016)

A Combination Microbicide Gel Protects Macaques Against Vaginal Simian Human Immunodeficiency Virus-Reverse Transcriptase Infection, But Only Partially Reduces Herpes Simplex Virus...

Por Hsu, Mayla, Aravantinou, Meropi, Menon, Radhika, Seidor, Samantha, Goldman, Daniel, Kenney, Jessica, Derby, Nina, Gettie, Agegnehu, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Fernández-Romero, Jose A., Zydowsky, Thomas M., Robbiani, Melissa
Publicado em 2014

A Macaque Model to Study Vaginal HSV-2/Immunodeficiency Virus Co-Infection and the Impact of HSV-2 on Microbicide Efficacy

Por Crostarosa, Federica, Aravantinou, Meropi, Akpogheneta, Onome J., Jasny, Edith, Shaw, Andrew, Kenney, Jessica, Piatak, Michael, Lifson, Jeffrey D., Teitelbaum, Aaron, Hu, Lieyu, Chudolij, Anne, Zydowsky, Thomas M., Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa
Publicado em 2009

MIV-150-Containing Intravaginal Rings Protect Macaque Vaginal Explants against SHIV-RT Infection

Por Ouattara, Louise A., Barnable, Patrick, Mawson, Paul, Seidor, Samantha, Zydowsky, Thomas M., Kizima, Larisa, Rodriguez, Aixa, Fernández-Romero, José A., Cooney, Michael L., Roberts, Kevin D., Gettie, Agegnehu, Blanchard, James, Robbiani, Melissa, Teleshova, Natalia
Publicado em 2014

In Vitro and In Vivo Evaluation of Two Carrageenan-based Formulations to Prevent HPV Acquisition

Por Rodríguez, Aixa, Kleinbeck, Kyle, Mizenina, Olga, Kizima, Larisa, Levendosky, Keith, Jean-Pierre, Ninochka, Villegas, Guillermo, Ford, Brian E., Cooney, Michael L., Teleshova, Natalia, Robbiani, Melissa, Herold, Betsy C., Zydowsky, Thomas, Romero, José A. Fernández
Publicado em 2014

First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence, and Pharmacodynamics

Por Friedland, Barbara A., Hoesley, Craig J., Plagianos, Marlena, Hoskin, Elena, Zhang, Shimin, Teleshova, Natalia, Alami, Mohcine, Novak, Lea, Kleinbeck, Kyle R., Katzen, Lauren L., Zydowsky, Thomas M., Fernández-Romero, José A., Creasy, George W.
Publicado no J Acquir Immune Defic Syndr (2016)

Zinc Acetate/Carrageenan Gels Exhibit Potent Activity In Vivo against High-Dose Herpes Simplex Virus 2 Vaginal and Rectal Challenge

Por Fernández-Romero, José A., Abraham, Ciby J., Rodriguez, Aixa, Kizima, Larisa, Jean-Pierre, Ninochka, Menon, Radhika, Begay, Othell, Seidor, Samantha, Ford, Brian E., Gil, Pedro I., Peters, Jennifer, Katz, David, Robbiani, Melissa, Zydowsky, Thomas M.
Publicado em 2012

A Single Dose of a MIV-150/Zinc Acetate Gel Provides 24 h of Protection Against Vaginal Simian Human Immunodeficiency Virus Reverse Transcriptase Infection, with More Limited Prote...

Por Kenney, Jessica, Singer, Rachel, Derby, Nina, Aravantinou, Meropi, Abraham, Ciby J., Menon, Radhika, Seidor, Samantha, Zhang, Shimin, Gettie, Agegnehu, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Fernández-Romero, José A., Zydowsky, Thomas M., Robbiani, Melissa
Publicado em 2012