Zinc Acetate/Carrageenan Gels Exhibit Potent Activity In Vivo against High-Dose Herpes Simplex Virus 2 Vaginal and Rectal Challenge

Topical microbicides that block the sexual transmission of HIV and herpes simplex virus 2 (HSV-2) are desperately needed to reduce the incidence of HIV infections worldwide. Previously we completed phase 3 testing of the carrageenan-based gel Carraguard. Although the trial did not show that Carragua...

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Autors principals: Fernández-Romero, José A., Abraham, Ciby J., Rodriguez, Aixa, Kizima, Larisa, Jean-Pierre, Ninochka, Menon, Radhika, Begay, Othell, Seidor, Samantha, Ford, Brian E., Gil, Pedro I., Peters, Jennifer, Katz, David, Robbiani, Melissa, Zydowsky, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256046/
https://ncbi.nlm.nih.gov/pubmed/22064530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05461-11
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