A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

Mucosal HIV-1 transmission is inefficient. However, certain viral and host characteristics may play a role in facilitating HIV acquisition and systemic expansion. Cells expressing high levels of integrin α(4)β(7) have been implicated in favoring the transmission process and the infusion of an anti-α...

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Vydáno v:PLoS Pathog
Hlavní autoři: Arrode-Brusés, Géraldine, Goode, Diana, Kleinbeck, Kyle, Wilk, Jolanta, Frank, Ines, Byrareddy, Siddappa, Arthos, James, Grasperge, Brooke, Blanchard, James, Zydowsky, Thomas, Gettie, Agegnehu, Martinelli, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922556/
https://ncbi.nlm.nih.gov/pubmed/27348748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005720
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