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A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
Mucosal HIV-1 transmission is inefficient. However, certain viral and host characteristics may play a role in facilitating HIV acquisition and systemic expansion. Cells expressing high levels of integrin α(4)β(7) have been implicated in favoring the transmission process and the infusion of an anti-α...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922556/ https://ncbi.nlm.nih.gov/pubmed/27348748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005720 |
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