The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators

le Huang, Xianhai, Aslanian, Robert, Zhou, Wei, Zhu, Xiaohong, Qin, Jun, Greenlee, William, Zhu, Zhaoning, Zhang, Lili, Hyde, Lynn, Chu, Inhou, Cohen-Williams, Mary, Palani, Anandan
Foilsithe 2010

Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators

le Qin, Jun, Zhou, Wei, Huang, Xianhai, Dhondi, Pawan, Palani, Anandan, Aslanian, Robert, Zhu, Zhaoning, Greenlee, William, Cohen-Williams, Mary, Jones, Nicholas, Hyde, Lynn, Zhang, Lili
Foilsithe 2011

Discovery of a Tetrahydrobenzisoxazole Series of γ-Secretase Modulators

le Zhao, Zhiqiang, Pissarnitski, Dmitri A., Huang, Xianhai, Palani, Anandan, Zhu, Zhaoning, Greenlee, William J., Hyde, Lynn A., Song, Lixin, Terracina, Giuseppe, Zhang, Lili, Parker, Eric M.
Foilsithe in ACS Med Chem Lett (2017)

Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease

le Huang, Xianhai, Zhou, Wei, Liu, Xiaoxiang, Li, Hongmei, Sun, George, Mandal, Mihirbaran, Vicarel, Monica, Zhu, Xiaohong, Bennett, Chad, McCraken, Troy, Pissarnitski, Dmitri, Zhao, Zhiqiang, Cole, David, Gallo, Gioconda, Zhu, Zhaoning, Palani, Anandan, Aslanian, Robert, Clader, John, Czarniecki, Michael, Greenlee, William, Burnett, Duane, Cohen-Williams, Mary, Hyde, Lynn, Song, Lixin, Zhang, Lili, Chu, Inhou, Buevich, Alexei
Foilsithe 2012

Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS Aβ Reduction

le Stamford, Andrew W., Scott, Jack D., Li, Sarah W., Babu, Suresh, Tadesse, Dawit, Hunter, Rachael, Wu, Yusheng, Misiaszek, Jeffrey, Cumming, Jared N., Gilbert, Eric J., Huang, Chunli, McKittrick, Brian A., Hong, Liwu, Guo, Tao, Zhu, Zhaoning, Strickland, Corey, Orth, Peter, Voigt, Johannes H., Kennedy, Matthew E., Chen, Xia, Kuvelkar, Reshma, Hodgson, Robert, Hyde, Lynn A., Cox, Kathleen, Favreau, Leonard, Parker, Eric M., Greenlee, William J.
Foilsithe 2012