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Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators
[Image: see text] The synthesis and structure−activity relationship of a novel series of pyrazolopyridines are reported. These compounds represent a new class of γ-secretase modulators that demonstrate good in vitro potency in inhibiting Aβ(42) production. Examples with statistically significant in...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018171/ https://ncbi.nlm.nih.gov/pubmed/24900332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000438 |
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