The splicing regulator PTBP2 is an AID interacting protein and promotes binding of AID to switch region DNA

par Nowak, Urszula, Matthews, Allysia, Zheng, Simin, Chaudhuri, Jayanta
Publié 2010

Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury

par Niu, Xiaoli, Zheng, Simin, Liu, Hongtao, Li, Siyuan
Publié dans Mol Med Rep (2018)

Regulation of Immunoglobulin Class-Switch Recombination: Choreography of Noncoding Transcription, Targeted DNA Deamination, and Long-Range DNA Repair

par Matthews, Allysia J., Zheng, Simin, DiMenna, Lauren J., Chaudhuri, Jayanta
Publié 2014

CtIP promotes microhomology-mediated alternative end-joining during class switch recombination

par Lee-Theilen, Mieun, Matthews, Allysia J., Kelly, Dierdre, Zheng, Simin, Chaudhuri, Jayanta
Publié 2010

Hypoxia-induced brain cell damage in male albino wistar rat

par Niu, Xiaoli, Li, Siyuan, Zheng, Simin, Xiong, Hongfei, Lv, Junlin, Zhang, Huijuan, Liu, Hongtao
Publié dans Saudi J Biol Sci (2018)

NME proteins regulate class switch recombination

par Zheng, Simin, Kusnadi, Anthony, Choi, Jee Eun, Vuong, Bao Q., Rhodes, Daniela, Chaudhuri, Jayanta
Publié dans FEBS Lett (2018)

Non-coding RNA generated following lariat-debranching mediates targeting of AID to DNA

par Zheng, Simin, Vuong, Bao Q., Vaidyanathan, Bharat, Lin, Jia-Yu, Huang, Feng-Ting, Chaudhuri, Jayanta
Publié dans Cell (2015)

The uncharacterized SANT and BTB domain-containing protein SANBR inhibits class switch recombination

par Zheng, Simin, Matthews, Allysia J., Rahman, Numa, Herrick-Reynolds, Kayleigh, Sible, Emily, Choi, Jee Eun, Wishnie, Alec, Ng, Yan Kee, Rhodes, Daniela, Elledge, Stephen J., Vuong, Bao Q.
Publié dans J Biol Chem (2021)

DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells

par Lim, Jung-Yeon, Duttke, Sascha H., Baker, Turner S., Lee, Jihye, Gambino, Kristyne J., Venturini, Nicholas J., Ho, Jessica Sook Yuin, Zheng, Simin, Fstkchyan, Yesai S., Pillai, Vinodh, Fajgenbaum, David C., Marazzi, Ivan, Benner, Christopher, Byun, Minji
Publié dans J Exp Med (2021)

A Quantitative Genetic Interaction Map of HIV Infection

par Gordon, David E., Watson, Ariane, Roguev, Assen, Zheng, Simin, Jang, Gwendolyn M., Kane, Joshua, Xu, Jiewei, Guo, Jeffrey Z., Stevenson, Erica, Swaney, Danielle L., Franks-Skiba, Kathy, Verschueren, Erik, Shales, Michael, Crosby, David C., Frankel, Alan D., Marson, Alexander, Marazzi, Ivan, Cagney, Gerard, Krogan, Nevan J.
Publié dans Mol Cell (2020)

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

par Ho, Jessica Sook Yuin, Angel, Matthew, Ma, Yixuan, Sloan, Elizabeth, Wang, Guojun, Martinez-Romero, Carles, Alenquer, Marta, Roudko, Vladimir, Chung, Liliane, Zheng, Simin, Chang, Max, Fstkchyan, Yesai, Clohisey, Sara, Dinan, Adam M., Gibbs, James, Gifford, Robert, Shen, Rong, Gu, Quan, Irigoyen, Nerea, Campisi, Laura, Huang, Cheng, Zhao, Nan, Jones, Joshua D., van Knippenberg, Ingeborg, Zhu, Zeyu, Moshkina, Natasha, Meyer, Léa, Noel, Justine, Peralta, Zuleyma, Rezelj, Veronica, Kaake, Robyn, Rosenberg, Brad, Wang, Bo, Wei, Jiajie, Paessler, Slobodan, Wise, Helen M., Johnson, Jeffrey, Vannini, Alessandro, Amorim, Maria João, Baillie, J. Kenneth, Miraldi, Emily R., Benner, Christopher, Brierley, Ian, Digard, Paul, Łuksza, Marta, Firth, Andrew E., Krogan, Nevan, Greenbaum, Benjamin D., MacLeod, Megan K., van Bakel, Harm, Garcìa-Sastre, Adolfo, Yewdell, Jonathan W., Hutchinson, Edward, Marazzi, Ivan
Publié dans Cell (2020)

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

par Yuin Ho, Jessica Sook, Wing-Yee Mok, Bobo, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A, Gaudreault, Natasha N, Meekins, David A, Indran, Sabarish V., Morozov, Igor, Trujillo, Jessie D, Fstkchyan, Yesai S, Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J, Lau, Siu-Ying, Liu, Honglian, Junxia Zhang, Anna, Chak-Yiu Lee, Andrew, Liu, Wen-Chun, Aydillo, Teresa, Salom Melo, Betsaida, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A., Moreira, Andre L., Carossino, Mariano, Balasuriya, Udeni B R, Byun, Minji, Miraldi, Emily R, Albrecht, Randy A, Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K, Jeyasekharan, Anand D, TenOever, Benjamin R, Spivakov, Mikhail, Weirauch, Matthew T, Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A, Marazzi, Ivan
Publié dans bioRxiv (2020)

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

par Ho, Jessica Sook Yuin, Mok, Bobo Wing-Yee, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A., Gaudreault, Natasha N., Meekins, David A., Indran, Sabarish V., Morozov, Igor, Trujillo, Jessie D., Fstkchyan, Yesai S., Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J., Lau, Siu-Ying, Liu, Honglian, Zhang, Anna Junxia, Lee, Andrew Chak-Yiu, Liu, Wen-Chun, Jangra, Sonia, Escalera, Alba, Aydillo, Teresa, Melo, Betsaida Salom, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A., Moreira, Andre L., Carossino, Mariano, Balasuriya, Udeni B.R., Byun, Minji, Albrecht, Randy A., Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K., Miraldi, Emily R., Jeyasekharan, Anand D., TenOever, Benjamin R., Spivakov, Mikhail, Weirauch, Matthew T., Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A., Marazzi, Ivan
Publié dans Cell (2021)