Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

od Zake, Darta Maija, Kurlovics, Janis, Zaharenko, Linda, Komasilovs, Vitalijs, Klovins, Janis, Stalidzans, Egils
Wydane w PLoS One (2021)

Genome Database of the Latvian Population (LGDB): Design, Goals, and Primary Results

od Rovite, Vita, Wolff-Sagi, Yael, Zaharenko, Linda, Nikitina-Zake, Liene, Grens, Elmars, Klovins, Janis
Wydane w J Epidemiol (2018)

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

od Ustinova, Monta, Peculis, Raitis, Rescenko, Raimonds, Rovite, Vita, Zaharenko, Linda, Elbere, Ilze, Silamikele, Laila, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Wydane w BMC Med Genomics (2021)

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

od Elbere, Ilze, Kalnina, Ineta, Silamikelis, Ivars, Konrade, Ilze, Zaharenko, Linda, Sekace, Kristine, Radovica-Spalvina, Ilze, Fridmanis, Davids, Gudra, Dita, Pirags, Valdis, Klovins, Janis
Wydane w PLoS One (2018)

Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients

od Elbere, Ilze, Silamikelis, Ivars, Dindune, Ilze Izabella, Kalnina, Ineta, Ustinova, Monta, Zaharenko, Linda, Silamikele, Laila, Rovite, Vita, Gudra, Dita, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Wydane w PLoS One (2020)

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

od Elbere, Ilze, Silamikelis, Ivars, Ustinova, Monta, Kalnina, Ineta, Zaharenko, Linda, Peculis, Raitis, Konrade, Ilze, Ciuculete, Diana Maria, Zhukovsky, Christina, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Pirags, Valdis, Schiöth, Helgi B., Klovins, Janis
Wydane w Clin Epigenetics (2018)

Extending the Minimum Information About BIobank Data Sharing Terminology to Describe Samples, Sample Donors, and Events

od Eklund, Niina, Andrianarisoa, Ny Haingo, van Enckevort, Esther, Anton, Gabriele, Debucquoy, Annelies, Müller, Heimo, Zaharenko, Linda, Engels, Cäcilia, Ebert, Lars, Neumann, Michael, Geeraert, Joachim, T'Joen, Veronique, Demski, Hans, Caboux, Élodie, Proynova, Rumyana, Parodi, Barbara, Mate, Sebastian, van Iperen, Erik, Merino-Martinez, Roxana, Quinlan, Philip R., Holub, Petr, Silander, Kaisa
Wydane w Biopreserv Biobank (2020)

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

od Spjuth, Ola, Krestyaninova, Maria, Hastings, Janna, Shen, Huei-Yi, Heikkinen, Jani, Waldenberger, Melanie, Langhammer, Arnulf, Ladenvall, Claes, Esko, Tõnu, Persson, Mats-Åke, Heggland, Jon, Dietrich, Joern, Ose, Sandra, Gieger, Christian, Ried, Janina S, Peters, Annette, Fortier, Isabel, de Geus, Eco JC, Klovins, Janis, Zaharenko, Linda, Willemsen, Gonneke, Hottenga, Jouke-Jan, Litton, Jan-Eric, Karvanen, Juha, Boomsma, Dorret I, Groop, Leif, Rung, Johan, Palmgren, Juni, Pedersen, Nancy L, McCarthy, Mark I, van Duijn, Cornelia M, Hveem, Kristian, Metspalu, Andres, Ripatti, Samuli, Prokopenko, Inga, Harris, Jennifer R
Wydane w Eur J Hum Genet (2016)

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

od Zhou, Kaixin, Yee, Sook Wah, Seiser, Eric L, van Leeuwen, Nienke, Tavendale, Roger, Bennett, Amanda J, Groves, Christopher J, Coleman, Ruth L, van der Heijden, Amber A, Beulens, Joline W, de Keyser, Catherine E, Zaharenko, Linda, Rotroff, Daniel M, Out, Mattijs, Jablonski, Kathleen A, Chen, Ling, Javorský, Martin, Židzik, Jozef, Levin, Albert M, Williams, L Keoki, Dujic, Tanja, Semiz, Sabina, Kubo, Michiaki, Chien, Huan-Chieh, Maeda, Shiro, Witte, John S, Wu, Longyang, Tkáč, Ivan, Kooy, Adriaan, van Schaik, Ron H N, Stehouwer, Coen D A, Logie, Lisa, Sutherland, Calum, Klovins, Janis, Pirags, Valdis, Hofman, Albert, Stricker, Bruno H, Motsinger-Reif, Alison A, Wagner, Michael J, Innocenti, Federico, 't Hart, Leen M, Holman, Rury R, McCarthy, Mark I, Hedderson, Monique M, Palmer, Colin N A, Florez, Jose C, Giacomini, Kathleen M, Pearson, Ewan R
Wydane w Nat Genet (2016)