Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

ανά Zake, Darta Maija, Kurlovics, Janis, Zaharenko, Linda, Komasilovs, Vitalijs, Klovins, Janis, Stalidzans, Egils
Τόπος έκδοσης PLoS One (2021)

Genome Database of the Latvian Population (LGDB): Design, Goals, and Primary Results

ανά Rovite, Vita, Wolff-Sagi, Yael, Zaharenko, Linda, Nikitina-Zake, Liene, Grens, Elmars, Klovins, Janis
Τόπος έκδοσης J Epidemiol (2018)

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

ανά Ustinova, Monta, Peculis, Raitis, Rescenko, Raimonds, Rovite, Vita, Zaharenko, Linda, Elbere, Ilze, Silamikele, Laila, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Τόπος έκδοσης BMC Med Genomics (2021)

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

ανά Elbere, Ilze, Kalnina, Ineta, Silamikelis, Ivars, Konrade, Ilze, Zaharenko, Linda, Sekace, Kristine, Radovica-Spalvina, Ilze, Fridmanis, Davids, Gudra, Dita, Pirags, Valdis, Klovins, Janis
Τόπος έκδοσης PLoS One (2018)

Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients

ανά Elbere, Ilze, Silamikelis, Ivars, Dindune, Ilze Izabella, Kalnina, Ineta, Ustinova, Monta, Zaharenko, Linda, Silamikele, Laila, Rovite, Vita, Gudra, Dita, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Τόπος έκδοσης PLoS One (2020)

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

ανά Elbere, Ilze, Silamikelis, Ivars, Ustinova, Monta, Kalnina, Ineta, Zaharenko, Linda, Peculis, Raitis, Konrade, Ilze, Ciuculete, Diana Maria, Zhukovsky, Christina, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Pirags, Valdis, Schiöth, Helgi B., Klovins, Janis
Τόπος έκδοσης Clin Epigenetics (2018)

Extending the Minimum Information About BIobank Data Sharing Terminology to Describe Samples, Sample Donors, and Events

ανά Eklund, Niina, Andrianarisoa, Ny Haingo, van Enckevort, Esther, Anton, Gabriele, Debucquoy, Annelies, Müller, Heimo, Zaharenko, Linda, Engels, Cäcilia, Ebert, Lars, Neumann, Michael, Geeraert, Joachim, T'Joen, Veronique, Demski, Hans, Caboux, Élodie, Proynova, Rumyana, Parodi, Barbara, Mate, Sebastian, van Iperen, Erik, Merino-Martinez, Roxana, Quinlan, Philip R., Holub, Petr, Silander, Kaisa
Τόπος έκδοσης Biopreserv Biobank (2020)

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

ανά Spjuth, Ola, Krestyaninova, Maria, Hastings, Janna, Shen, Huei-Yi, Heikkinen, Jani, Waldenberger, Melanie, Langhammer, Arnulf, Ladenvall, Claes, Esko, Tõnu, Persson, Mats-Åke, Heggland, Jon, Dietrich, Joern, Ose, Sandra, Gieger, Christian, Ried, Janina S, Peters, Annette, Fortier, Isabel, de Geus, Eco JC, Klovins, Janis, Zaharenko, Linda, Willemsen, Gonneke, Hottenga, Jouke-Jan, Litton, Jan-Eric, Karvanen, Juha, Boomsma, Dorret I, Groop, Leif, Rung, Johan, Palmgren, Juni, Pedersen, Nancy L, McCarthy, Mark I, van Duijn, Cornelia M, Hveem, Kristian, Metspalu, Andres, Ripatti, Samuli, Prokopenko, Inga, Harris, Jennifer R
Τόπος έκδοσης Eur J Hum Genet (2016)

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

ανά Zhou, Kaixin, Yee, Sook Wah, Seiser, Eric L, van Leeuwen, Nienke, Tavendale, Roger, Bennett, Amanda J, Groves, Christopher J, Coleman, Ruth L, van der Heijden, Amber A, Beulens, Joline W, de Keyser, Catherine E, Zaharenko, Linda, Rotroff, Daniel M, Out, Mattijs, Jablonski, Kathleen A, Chen, Ling, Javorský, Martin, Židzik, Jozef, Levin, Albert M, Williams, L Keoki, Dujic, Tanja, Semiz, Sabina, Kubo, Michiaki, Chien, Huan-Chieh, Maeda, Shiro, Witte, John S, Wu, Longyang, Tkáč, Ivan, Kooy, Adriaan, van Schaik, Ron H N, Stehouwer, Coen D A, Logie, Lisa, Sutherland, Calum, Klovins, Janis, Pirags, Valdis, Hofman, Albert, Stricker, Bruno H, Motsinger-Reif, Alison A, Wagner, Michael J, Innocenti, Federico, 't Hart, Leen M, Holman, Rury R, McCarthy, Mark I, Hedderson, Monique M, Palmer, Colin N A, Florez, Jose C, Giacomini, Kathleen M, Pearson, Ewan R
Τόπος έκδοσης Nat Genet (2016)