Neuropilin 1 Is Essential for Gastrointestinal Smooth Muscle Contractility and Motility in Aged Mice

Por Yamaji, Maiko, Mahmoud, Marwa, Evans, Ian M., Zachary, Ian C.
Publicado no PLoS One (2015)

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

Por Herzog, Birger, Pellet-Many, Caroline, Britton, Gary, Hartzoulakis, Basil, Zachary, Ian C.
Publicado em 2011

Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells

Por Jopling, Helen M., Odell, Adam, Hooper, Nigel M., Zachary, Ian C., Walker, John H., Ponnambalam, Sreenivasan
Publicado em 2009

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130(Cas)

Por Pellet-Many, Caroline, Frankel, Paul, Evans, Ian M., Herzog, Birger, Jünemann-Ramírez, Manfred, Zachary, Ian C.
Publicado em 2011

Neuropilin-1 Signaling through p130(Cas) Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells

Por Evans, Ian M., Yamaji, Maiko, Britton, Gary, Pellet-Many, Caroline, Lockie, Claire, Zachary, Ian C., Frankel, Paul
Publicado em 2011

Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells

Por Evans, Ian M., Bagherzadeh, Azadeh, Charles, Mark, Raynham, Tony, Ireson, Chris, Boakes, Alexandra, Kelland, Lloyd, Zachary, Ian C.
Publicado em 2010

Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway

Por Frankel, Paul, Pellet-Many, Caroline, Lehtolainen, Pauliina, D'Abaco, Giovanna M, Tickner, Michelle L, Cheng, Lili, Zachary, Ian C
Publicado em 2008

Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression

Por Miyauchi, Jeremy T., Chen, Danling, Choi, Matthew, Nissen, Jillian C., Shroyer, Kenneth R., Djordevic, Snezana, Zachary, Ian C., Selwood, David, Tsirka, Stella E.
Publicado no Oncotarget (2016)

Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling

Por Frolov, Antonina, Evans, Ian M., Li, Ningning, Sidlauskas, Kastytis, Paliashvili, Ketevan, Lockwood, Nicola, Barrett, Angela, Brandner, Sebastian, Zachary, Ian C., Frankel, Paul
Publicado no Sci Rep (2016)

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation

Por Jopling, Helen M., Odell, Adam F., Pellet-Many, Caroline, Latham, Antony M., Frankel, Paul, Sivaprasadarao, Asipu, Walker, John H., Zachary, Ian C., Ponnambalam, Sreenivasan
Publicado em 2014

Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis

Por Evans, Ian M., Kennedy, Susan A., Paliashvili, Ketevan, Santra, Tapesh, Yamaji, Maiko, Lovering, Ruth C., Britton, Gary, Frankel, Paul, Kolch, Walter, Zachary, Ian C.
Publicado no Mol Cell Proteomics (2017)

Uteroplacental Adenovirus Vascular Endothelial Growth Factor Gene Therapy Increases Fetal Growth Velocity in Growth-Restricted Sheep Pregnancies

Por Carr, David J., Wallace, Jacqueline M., Aitken, Raymond P., Milne, John S., Mehta, Vedanta, Martin, John F., Zachary, Ian C., Peebles, Donald M., David, Anna L.
Publicado em 2014

A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair

Por Bruns, Alexander F., Yuldasheva, Nadira, Latham, Antony M., Bao, Leyuan, Pellet-Many, Caroline, Frankel, Paul, Stephen, Sam L., Howell, Gareth J., Wheatcroft, Stephen B., Kearney, Mark T., Zachary, Ian C., Ponnambalam, Sreenivasan
Publicado em 2012

VEGF-A isoforms differentially regulate ATF-2–dependent VCAM-1 gene expression and endothelial–leukocyte interactions

Por Fearnley, Gareth W., Odell, Adam F., Latham, Antony M., Mughal, Nadeem A., Bruns, Alexander F., Burgoyne, Nicholas J., Homer-Vanniasinkam, Shervanthi, Zachary, Ian C., Hollstein, Monica C., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Publicado em 2014

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

Por Fearnley, Gareth W., Smith, Gina A., Abdul-Zani, Izma, Yuldasheva, Nadira, Mughal, Nadeem A., Homer-Vanniasinkam, Shervanthi, Kearney, Mark T., Zachary, Ian C., Tomlinson, Darren C., Harrison, Michael A., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Publicado no Biol Open (2016)