VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell responses that control vascular development. Multiple isoforms of VEGF-A can elicit differential signal transduction and endoth...

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Veröffentlicht in:Biol Open
Hauptverfasser: Fearnley, Gareth W., Smith, Gina A., Abdul-Zani, Izma, Yuldasheva, Nadira, Mughal, Nadeem A., Homer-Vanniasinkam, Shervanthi, Kearney, Mark T., Zachary, Ian C., Tomlinson, Darren C., Harrison, Michael A., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874356/
https://ncbi.nlm.nih.gov/pubmed/27044325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.017434
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