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Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells

OBJECTIVE: Vascular endothelial growth factor receptor 2 (VEGFR2) is a receptor tyrosine kinase that regulates vascular physiology. However, mechanism(s) by which VEGFR2 signaling and trafficking is co-ordinated are not clear. Here, we have tested endocytic Rab GTPases for regulation of VEGFR2 traff...

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Bibliografiska uppgifter
Huvudupphovsmän: Jopling, Helen M., Odell, Adam, Hooper, Nigel M., Zachary, Ian C., Walker, John H., Ponnambalam, Sreenivasan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704050/
https://ncbi.nlm.nih.gov/pubmed/19372461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.186239
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