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Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

Vascular endothelial growth factor receptor-2 (VEGFR2) and its ligands (VEGFs) are crucial players in vasculogenesis and angiogenesis. General blocking of this signaling system with antibodies or small molecule inhibitors is an established strategy to treat cancer and age-related macular degeneratio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xie, Ye, Mansouri, Maysam, Rizk, Aurélien, Berger, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746989/
https://ncbi.nlm.nih.gov/pubmed/31527750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49646-4
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