Wnt pathway regulation of intestinal stem cells

Por Mah, Amanda T., Yan, Kelley S., Kuo, Calvin J.
Publicado no J Physiol (2016)

Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain

Por Zeng, Lei, Zhang, Qiang, Yan, Kelley, Zhou, Ming-Ming
Publicado em 2011

Engineering of Three-Dimensional Microenvironments to Promote Contractile Behavior in Primary Intestinal Organoids

Por DiMarco, Rebecca L., Su, James, Yan, Kelley S., Dewi, Ruby, Kuo, Calvin J., Heilshorn, Sarah C.
Publicado em 2014

Dclk1-expressing tuft cells: critical modulators of the intestinal niche?

Por Middelhoff, Moritz, Westphalen, C. Benedikt, Hayakawa, Yoku, Yan, Kelley S., Gershon, Michael D., Wang, Timothy C., Quante, Michael
Publicado no Am J Physiol Gastrointest Liver Physiol (2017)

Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury

Por Bohin, Natacha, McGowan, Kevin P., Keeley, Theresa M., Carlson, Elizabeth A., Yan, Kelley S., Samuelson, Linda C.
Publicado no Cell Mol Gastroenterol Hepatol (2020)

Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors

Por Dhalluin, Christophe, Yan, Kelley S., Plotnikova, Olga, Lee, Kyung W., Zeng, Lei, Kuti, Miklos, Mujtaba, Shiraz, Goldfarb, Mitchell P., Zhou, Ming-Ming
Publicado no Mol Cell (2000)

Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling

Por Lim, Xinhong, Tan, Si Hui, Koh, Winston Lian Chye, Chau, Rosanna Man Wah, Yan, Kelley S., Kuo, Calvin J., van Amerongen, Renée, Klein, Allon Moshe, Nusse, Roel
Publicado em 2013

Restriction of intestinal stem cell expansion and the regenerative response by YAP

Por Barry, Evan R., Morikawa, Teppei, Butler, Brian L., Shrestha, Kriti, de la Rosa, Rosemarie, Yan, Kelley S., Fuchs, Charles S., Magness, Scott T., Smits, Ron, Ogino, Shuji, Kuo, Calvin J., Camargo, Fernando D.
Publicado em 2012

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

Por Yan, Kelley S., Chia, Luis A., Li, Xingnan, Ootani, Akifumi, Su, James, Lee, Josephine Y., Su, Nan, Luo, Yuling, Heilshorn, Sarah C., Amieva, Manuel R., Sangiorgi, Eugenio, Capecchi, Mario R., Kuo, Calvin J.
Publicado em 2012

Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

Por Middelhoff, Moritz, Nienhüser, Henrik, Valenti, Giovanni, Maurer, H. Carlo, Hayakawa, Yoku, Takahashi, Ryota, Kim, Woosook, Jiang, Zhengyu, Malagola, Ermanno, Cuti, Krystle, Tailor, Yagnesh, Zamechek, Leah B., Renz, Bernhard W., Quante, Michael, Yan, Kelley S., Wang, Timothy C.
Publicado no Nat Commun (2020)

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling

Por Janda, Claudia Y., Dang, Luke T., You, Changjiang, Chang, Junlei, de Lau, Wim, Zhong, Zhendong A., Yan, Kelley S., Marecic, Owen, Siepe, Dirk, Li, Xingnan, Moody, James D., Williams, Bart O., Clevers, Hans, Piehler, Jacob, Baker, David, Kuo, Calvin J., Garcia, K. Christopher
Publicado no Nature (2017)

BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice

Por Hayakawa, Yoku, Tsuboi, Mayo, Asfaha, Samuel, Kinoshita, Hiroto, Niikura, Ryota, Konishi, Mitsuru, Hata, Masahiro, Oya, Yukiko, Kim, Woosook, Middelhoff, Moritz, Hikiba, Yohko, Higashijima, Naoko, Ihara, Sozaburo, Ushiku, Tetsuo, Fukayama, Masashi, Tailor, Yagnesh, Hirata, Yoshihiro, Guha, Chandan, Yan, Kelley S., Koike, Kazuhiko, Wang, Timothy C.
Publicado no Gastroenterology (2018)

A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells

Por Magness, Scott T., Puthoff, Brent J., Crissey, Mary Ann, Dunn, James, Henning, Susan J., Houchen, Courtney, Kaddis, John S., Kuo, Calvin J., Li, Linheng, Lynch, John, Martin, Martin G., May, Randal, Niland, Joyce C., Olack, Barbara, Qian, Dajun, Stelzner, Matthias, Swain, John R., Wang, Fengchao, Wang, Jiafang, Wang, Xinwei, Yan, Kelley, Yu, Jian, Wong, Melissa H.
Publicado em 2013

Identification and Specification of the Mouse Skeletal Stem Cell

Por Chan, Charles K.F., Seo, Eun Young, Chen, James Y., Lo, David, McArdle, Adrian, Sinha, Rahul, Tevlin, Ruth, Seita, Jun, Vincent-Tompkins, Justin, Wearda, Taylor, Lu, Wan-Jin, Senarath-Yapa, Kshemendra, Chung, Michael T., Marecic, Owen, Tran, Misha, Yan, Kelley S., Upton, Rosalynd, Walmsley, Graham G., Lee, Andrew S., Sahoo, Debashis, Kuo, Calvin, Weissman, Irving L., Longaker, Michael T.
Publicado no Cell (2015)

Non-equivalence of Wnt and R-spondin ligands during Lgr5(+) intestinal stem cell self-renewal

Por Yan, Kelley S., Janda, Claudia Y., Chang, Junlei, Zheng, Grace X.Y., Larkin, Kathryn A., Luca, Vincent C., Chia, Luis A., Mah, Amanda T., Han, Arnold, Terry, Jessica M., Ootani, Akifumi, Roelf, Kelly, Lee, Mark, Yuan, Jenny, Li, Xiao, Bolen, Christopher R., Wilhelmy, Julie, Davies, Paige S., Ueno, Hiroo, von Furstenberg, Richard J., Belgrader, Phillip, Ziraldo, Solongo B., Ordonez, Heather, Henning, Susan J., Wong, Melissa H., Snyder, Michael P., Weissman, Irving L., Hsueh, Aaron J., Mikkelsen, Tarjei S., Garcia, K. Christopher, Kuo, Calvin J.
Publicado no Nature (2017)

Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity

Por Yan, Kelley S., Gevaert, Olivier, Zheng, Grace X.Y., Anchang, Benedict, Probert, Christopher S., Larkin, Kathryn A., Davies, Paige S., Cheng, Zhuan-fen, Kaddis, John S., Han, Arnold, Roelf, Kelly, Calderon, Ruben I., Cynn, Esther, Hu, Xiaoyi, Mandleywala, Komal, Wilhelmy, Julie, Grimes, Sue, Corney, David, Boutet, Stéphane C., Terry, Jessica M., Belgrader, Phillip, Ziraldo, Solongo B., Mikkelsen, Tarjei S., Wang, Fengchao, von Furstenberg, Richard J., Smith, Nicholas R., Chandrakesan, Parthasarathy, May, Randal, Chrissy, MaryAnn, Jain, Rajan, Cartwright, Christine A., Niland, Joyce C., Hong, Young-Kwon, Carrington, Jill, Breault, David, Epstein, Jonathan, Houchen, Courtney W., Lynch, John P., Martin, Martin G., Plevritis, Sylvia K., Curtis, Christina, Ji, Hanlee P., Li, Linheng, Henning, Susan J., Wong, Melissa H., Kuo, Calvin J.
Publicado no Cell Stem Cell (2017)