Peptide intra-tumor injection for cancer immunotherapy: Enhancement of tumor cell antigenicity is a novel and attractive strategy

Por Nobuoka, Daisuke, Yoshikawa, Toshiaki, Fujiwara, Toshiyoshi, Nakatsura, Tetsuya
Publicado em 2013

Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma

Por Ofuji, Kazuya, Saito, Keigo, Yoshikawa, Toshiaki, Nakatsura, Tetsuya
Publicado no J Hepatocell Carcinoma (2014)

A glypican-3-derived peptide vaccine against hepatocellular carcinoma

Por Sawada, Yu, Sakai, Mayuko, Yoshikawa, Toshiaki, Ofuji, Kazuya, Nakatsura, Tetsuya
Publicado em 2012

Peptide vaccines for hepatocellular carcinoma

Por Nobuoka, Daisuke, Yoshikawa, Toshiaki, Sawada, Yu, Fujiwara, Toshiyoshi, Nakatsura, Tetsuya
Publicado em 2013

Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy

Por YOSHIKAWA, TOSHIAKI, TAKAHARA, MASASHI, TOMIYAMA, MAI, NIEDA, MIE, MAEKAWA, RYUJI, NAKATSURA, TETSUYA
Publicado em 2014

Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes

Por SAWADA, YU, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, IWAMA, TATSUAKI, ENDO, ITARU, NAKATSURA, TETSUYA
Publicado no Int J Oncol (2014)

Identification of an H2-K(b) or H2-D(b) restricted and glypican-3-derived cytotoxic T-lymphocyte epitope peptide

Por IWAMA, TATSUAKI, HORIE, KAZUTAKA, YOSHIKAWA, TOSHIAKI, NOBUOKA, DAISUKE, SHIMOMURA, MANAMI, SAWADA, YU, NAKATSURA, TETSUYA
Publicado em 2013

Cancer immunotherapy‐targeted glypican‐3 or neoantigens

Por Shimizu, Yasuhiro, Suzuki, Toshihiro, Yoshikawa, Toshiaki, Tsuchiya, Nobuhiro, Sawada, Yu, Endo, Itaru, Nakatsura, Tetsuya
Publicado no Cancer Sci (2018)

Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican-3-derived peptide

Por TADA, YOSHITAKA, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, SAWADA, YU, SAKAI, MAYUKO, SHIRAKAWA, HIROFUMI, NOBUOKA, DAISUKE, NAKATSURA, TETSUYA
Publicado em 201

A peptide antigen derived from EGFR T790M is immunogenic in non-small cell lung cancer

Por OFUJI, KAZUYA, TADA, YOSHITAKA, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, YOSHIMURA, MAYUKO, SAITO, KEIGO, NAKAMOTO, YASUNARI, NAKATSURA, TETSUYA
Publicado no Int J Oncol (2014)

Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma

Por Tsuchiya, Nobuhiro, Yoshikawa, Toshiaki, Fujinami, Norihiro, Saito, Keigo, Mizuno, Shoichi, Sawada, Yu, Endo, Itaru, Nakatsura, Tetsuya
Publicado no Oncoimmunology (2017)

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

Por Fujinami, Norihiro, Yoshikawa, Toshiaki, Sawada, Yu, Shimomura, Manami, Iwama, Tatsuaki, Sugai, Shiori, Kitano, Shigehisa, Uemura, Yasushi, Nakatsura, Tetsuya
Publicado no Biochem Biophys Rep (2016)

Remarkable tumor lysis in a hepatocellular carcinoma patient immediately following glypican-3-derived peptide vaccination: An autopsy case

Por Sawada, Yu, Yoshikawa, Toshiaki, Fujii, Satoshi, Mitsunaga, Shuichi, Nobuoka, Daisuke, Mizuno, Shoichi, Takahashi, Mari, Yamauchi, Chisako, Endo, Itaru, Nakatsura, Tetsuya
Publicado em 2013

Suppression of postsurgical recurrence of hepatocellular carcinoma treated with autologous formalin-fixed tumor vaccine, with special reference to glypican-3

Por Kawashima, Issei, Kawashima, Yuri, Matsuoka, Yasuo, Fujise, Kiyotaka, Sakai, Hideki, Takahashi, Mari, Yoshikawa, Toshiaki, Nakatsura, Tetsuya, Ishihara, Takeshi, Ohno, Tadao
Publicado no Clin Case Rep (2015)

Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate

Por SUGAI, SHIORI, YOSHIKAWA, TOSHIAKI, IWAMA, TATSUAKI, TSUCHIYA, NOBUHIRO, UEDA, NORIHIRO, FUJINAMI, NORIHIRO, SHIMOMURA, MANAMI, ZHANG, RONG, KANEKO, SHIN, UEMURA, YASUSHI, NAKATSURA, TETSUYA
Publicado no Int J Oncol (2016)

Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response

Por Sayem, Mohammad A., Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Irie, Atsushi, Tsukamoto, Hirotake, Senju, Satoru, Yuba, Eiji, Yoshikawa, Toshiaki, Kono, Kenji, Nakatsura, Tetsuya, Nishimura, Yasuharu
Publicado no Oncoimmunology (2015)

Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy

Por Nobuoka, Daisuke, Yoshikawa, Toshiaki, Takahashi, Mari, Iwama, Tatsuaki, Horie, Kazutaka, Shimomura, Manami, Suzuki, Shiro, Sakemura, Noriko, Nakatsugawa, Munehide, Sadamori, Hiroshi, Yagi, Takahito, Fujiwara, Toshiyoshi, Nakatsura, Tetsuya
Publicado em 2012

Detection and preliminary evaluation of circulating tumor cells in the peripheral blood of patients with eight types of cancer using a telomerase-specific adenovirus

Por YABUSAKI, MINA, SATO, JUN, KOHYAMA, ATSUSHI, KOJIMA, TAKASHI, NOBUOKA, DAISUKE, YOSHIKAWA, TOSHIAKI, SAWADA, YU, MURAKAMI, KATSUHIRO, GOHDA, KEIGO, OKEGAWA, TAKATSUGU, NAKAMURA, MASARU, TAKAMATSU, KIYOSHI, ITO, MASAAKI, KANEKO, KAZUHIRO, NAKATSURA, TETSUYA
Publicado em 2014

Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma

Por Ofuji, Kazuya, Saito, Keigo, Suzuki, Shiro, Shimomura, Manami, Shirakawa, Hirofumi, Nobuoka, Daisuke, Sawada, Yu, Yoshimura, Mayuko, Tsuchiya, Nobuhiro, Takahashi, Mari, Yoshikawa, Toshiaki, Tada, Yoshitaka, Konishi, Masaru, Takahashi, Shinichiro, Gotohda, Naoto, Nakamoto, Yasunari, Nakatsura, Tetsuya
Publicado no Oncotarget (2016)

Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors

Por Tsuchiya, Nobuhiro, Hosono, Ako, Yoshikawa, Toshiaki, Shoda, Kayoko, Nosaka, Kazuto, Shimomura, Manami, Hara, Junichi, Nitani, Chika, Manabe, Atsushi, Yoshihara, Hiroki, Hosoya, Yosuke, Kaneda, Hide, Kinoshita, Yoshiaki, Kohashi, Kenichi, Yoshimura, Kenichi, Fujinami, Norihiro, Saito, Keigo, Mizuno, Shoichi, Nakatsura, Tetsuya
Publicado no Oncoimmunology (2017)