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A glypican-3-derived peptide vaccine against hepatocellular carcinoma

The results of a Phase I clinical trial in which a glypican-3 (GPC3)-derived peptide was tested in advanced hepatocellular carcinoma patients point to a strong correlation between immunological and clinical responses. This commentary reviews our fundamental studies and clinical trials on the GPC3-de...

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Autors principals: Sawada, Yu, Sakai, Mayuko, Yoshikawa, Toshiaki, Ofuji, Kazuya, Nakatsura, Tetsuya
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518534/
https://ncbi.nlm.nih.gov/pubmed/23243625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21351
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