Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes

Novel treatment modalities are required urgently in patients with hepatocellular carcinoma (HCC). A vaccine that induces cytotoxic T lymphocytes (CTLs) is an ideal strategy for cancer, and glypican-3 (GPC3) is a potential option for HCC. Blocking the programmed death-1 (PD-1)/PD-L1 pathway is a rati...

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Publicado no:Int J Oncol
Main Authors: SAWADA, YU, YOSHIKAWA, TOSHIAKI, SHIMOMURA, MANAMI, IWAMA, TATSUAKI, ENDO, ITARU, NAKATSURA, TETSUYA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238729/
https://ncbi.nlm.nih.gov/pubmed/25354479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2737
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