Cd(2+), Mn(2+), Ni(2+) and Se(2+) toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2

Por Schmidt, Karyn, Wolfe, Devin M, Stiller, Barbara, Pearce, David A
Publicado em 2009

pH-dependent localization of Btn1p in the yeast model for Batten disease

Por Wolfe, Devin M., Padilla-Lopez, Sergio, Vitiello, Seasson Phillips, Pearce, David A.
Publicado em 2011

Autophagy failure in Alzheimer’s disease and the role of defective lysosomal acidification

Por Wolfe, Devin M., Lee, Ju-hyun, Kumar, Asok, Lee, Sooyeon, Orenstein, Samantha J., Nixon, Ralph A.
Publicado em 2013

β2-adrenergic agonists rescue lysosome acidification and function in PSEN1 deficiency by reversing defective ER to lysosome delivery of ClC-7

Por Lee, Ju-Hyun, Wolfe, Devin M., Darji, Sandipkumar, McBrayer, Mary Kate, Colacurcio, Daniel J., Kumar, Asok, Stavrides, Philip, Mohan, Panaiyur S., Nixon, Ralph A.
Publicado no J Mol Biol (2020)

Presenilin 1 maintains lysosomal Ca(2+) homeostasis by regulating vATPase-mediated lysosome acidification

Por Lee, Ju-Hyun, McBrayer, Mary Kate, Wolfe, Devin M., Haslett, Luke J., Kumar, Asok, Sato, Yutaka, Lie, Pearl P. Y., Mohan, Panaiyur, Coffey, Erin E., Kompella, Uday, Mitchell, Claire H., Lloyd-Evans, Emyr, Nixon, Ralph A.
Publicado no Cell Rep (2015)

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

Por Lee, Ju-Hyun, Yu, W. Haung, Kumar, Asok, Lee, Sooyeon, Mohan, Panaiyur S., Peterhoff, Corrinne M., Wolfe, Devin M., Martinez-Vicente, Marta, Massey, Ashish C., Sovak, Guy, Uchiyama, Yasuo, Westaway, David, Sisodia, Sangram S., Cuervo, Ana Maria, Nixon, Ralph A.
Publicado em 2010