Human Platelets and Factor XI: LOCALIZATION IN PLATELET MEMBRANES OF FACTOR XI-LIKE ACTIVITY AND ITS FUNCTIONAL DISTINCTION FROM PLASMA FACTOR XI

Por Lipscomb, Myatt S., Walsh, Peter N.
Publicado em 1979

An ordered sequential mechanism for Factor IX and Factor IXa binding to platelet receptors in the assembly of the Factor X-activating complex

Por Yang, Xia, Walsh, Peter N.
Publicado em 2005

Aspirin and the Prevention of Myocardial Infarction

Por Walsh, Peter N., Fratantoni, Joseph
Publicado em 1977

PAR-1-Stimulated Factor IXa Binding to a Small Platelet Subpopulation Requires a Pronounced and Sustained Increase of Cytoplasmic Calcium

Por London, Fredda S., Marcinkiewicz, Mariola, Walsh, Peter N.
Publicado em 2006

Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor

Por Navaneetham, Duraiswamy, Sinha, Dipali, Walsh, Peter N.
Publicado em 2010

A Catalytic Domain Exosite (Cys(527)-Cys(542)) in Factor XIa Mediates Binding to a Site on Activated Platelets

Por Miller, Tara N., Baird, T. Regan, Walsh, Peter N.
Publicado em 2007

Productive Recognition of Factor IX by Factor XIa Exosites Requires Disulfide Linkage between Heavy and Light Chains of Factor XIa

Por Marcinkiewicz, Mariola M., Sinha, Dipali, Walsh, Peter N.
Publicado em 2012

Molecular cloning and biochemical characterization of rabbit factor XI.

Por Sinha, Dipali, Marcinkiewicz, Mariola, Gailani, David, Walsh, Peter N
Publicado em 2002

Dimer Dissociation and Unfolding Mechanism of Coagulation Factor XI Apple 4 Domain: Spectroscopic and Mutational Analysis

Por Riley, Paul W., Cheng, Hong, Samuel, Dharmaraj, Roder, Heinrich, Walsh, Peter N.
Publicado em 2006

A Glu113Ala mutation within a factor VIII Ca(2+) binding site enhances cofactor interactions in factor Xase

Por Wakabayashi, Hironao, Su, Ya-Chi, Ahmad, Syed S., Walsh, Peter N., Fay, Philip J.
Publicado em 2005

P1 and P2′ site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor

Por Navaneetham, Duraiswamy, Wu, Wenman, Li, Hongbo, Sinha, Dipali, Tuma, Ronald F., Walsh, Peter N.
Publicado em 2013

Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin

Por Salameh, Moh'd A., Soares, Alexei S., Navaneetham, Duraiswamy, Sinha, Dipali, Walsh, Peter N., Radisky, Evette S.
Publicado em 2010

The Role of Factor XIa (FXIa) Catalytic Domain Exosite Residues in Substrate Catalysis and Inhibition by the Kunitz Protease Inhibitor Domain of Protease Nexin 2

Por Su, Ya-Chi, Miller, Tara N., Navaneetham, Duraiswamy, Schoonmaker, Robert T., Sinha, Dipali, Walsh, Peter N.
Publicado em 2011

The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis

Por Wu, Wenman, Li, Hongbo, Navaneetham, Duraiswamy, Reichenbach, Zachary W., Tuma, Ronald F., Walsh, Peter N.
Publicado em 2012

Factor XI contributes to thrombin generation in the absence of factor XII

Por Kravtsov, Dmitri V., Matafonov, Anton, Tucker, Erik I., Sun, Mao-fu, Walsh, Peter N., Gruber, Andras, Gailani, David
Publicado em 2009

The Amyloid Precursor Protein/Protease Nexin 2 Kunitz Inhibitor Domain Is a Highly Specific Substrate of Mesotrypsin

Por Salameh, Moh'd A., Robinson, Jessica L., Navaneetham, Duraiswamy, Sinha, Dipali, Madden, Benjamin J., Walsh, Peter N., Radisky, Evette S.
Publicado em 2010

Factor XI Homodimer Structure Is Essential for Normal Proteolytic Activation by Factor XIIa, Thrombin, and Factor XIa

Por Wu, Wenman, Sinha, Dipali, Shikov, Sergei, Yip, Calvin K., Walz, Thomas, Billings, Paul C., Lear, James D., Walsh, Peter N.
Publicado em 2008

Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation

Por Samuel, Dharmaraj, Cheng, Hong, Riley, Paul W., Canutescu, Adrian A., Nagaswami, Chandrasekaran, Weisel, John W., Bu, Zimei, Walsh, Peter N., Roder, Heinrich
Publicado em 2007