Advances in the proteomic discovery of novel therapeutic targets in cancer

Por Guo, Shanchun, Zou, Jin, Wang, Guangdi
Publicado em 2013

Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer

Por Jiang, Quan, Zheng, Shilong, Wang, Guangdi
Publicado em 2013

Glutathione peroxidases as oncotargets

Por Jiao, Yang, Wang, Yirong, Guo, Shanchun, Wang, Guangdi
Publicado no Oncotarget (2017)

In vitro metabolism of indomethacin morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB(2)) in rat liver microsomes

Por Zhang, Qiang, Ma, Peng, Cole, Richard B., Wang, Guangdi
Publicado em 2010

Optimal structural inference of signaling pathways from unordered and overlapping gene sets

Por Acharya, Lipi R., Judeh, Thair, Wang, Guangdi, Zhu, Dongxiao
Publicado em 2012

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

Por Mottamal, Madhusoodanan, Zheng, Shilong, Huang, Tien L., Wang, Guangdi
Publicado no Molecules (2015)

GREB1 Functions as a Growth Promoter and Is Modulated by IL6/STAT3 in Breast Cancer

Por Liu, Mingli, Wang, Guangdi, Gomez-Fernandez, Carmen R., Guo, Shanchun
Publicado em 2012

Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer

Por Jiang, Quan, Zhong, Qiu, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi
Publicado em 2012

Synergistic effects of combined treatment with histone deacetylase inhibitor suberoylanilide hydroxamic acid and TRAIL on human breast cancer cells

Por Zhou, Weiqiang, Feng, Xiuyan, Han Han, Guo, Shanchun, Wang, Guangdi
Publicado no Sci Rep (2016)

Boronic Prodrug of Endoxifen as an Effective Hormone Therapy for Breast Cancer

Por Zhang, Changde, Zhong, Qiu, Zhang, Qiang, Zheng, Shilong, Miele, Lucio, Wang, Guangdi
Publicado no Breast Cancer Res Treat (2015)

Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

Por Zhong, Qiu, Zhang, Changde, Zhang, Qiang, Miele, Lucio, Zheng, Shilong, Wang, Guangdi
Publicado no BMC Cancer (2015)

Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells

Por Guo, Shanchun, Liu, Mingli, Wang, Guangdi, Torroella-Kouri, Marta, Gonzalez-Perez, Ruben R.
Publicado em 2012

Ligands of Therapeutic Utility for the Liver X Receptors

Por Komati, Rajesh, Spadoni, Dominick, Zheng, Shilong, Sridhar, Jayalakshmi, Riley, Kevin E., Wang, Guangdi
Publicado no Molecules (2017)

Efficient Dual-Site Carbon Monoxide Electro-Catalysts via Interfacial Nano-Engineering

Por Liu, Zhen, Huang, Zhongyuan, Cheng, Feifei, Guo, Zhanhu, Wang, Guangdi, Chen, Xu, Wang, Zhe
Publicado no Sci Rep (2016)

Design and synthesis of novel hydroxyanthraquinone nitrogen mustard derivatives as potential anticancer agents via a bioisostere approach

Por Zhao, Li-Ming, Ma, Feng-Yan, Jin, Hai-Shan, Zheng, Shilong, Zhong, Qiu, Wang, Guangdi
Publicado no Eur J Med Chem (2015)

A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models

Por Li, Xiang, Chen, Guanglin, Zhang, Xiaojie, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Bioorg Med Chem Lett (2016)

3-O-Substituted-3′,4′,5′-trimethoxyflavonols: synthesis and cell-based evaluation as anti-prostate cancer agents

Por Li, Xiang, Lee, Maizie, Chen, Guanglin, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Bioorg Med Chem (2017)

One-pot synthesis of 1,4-dihydroxy-2-((E)-1-hydroxy-4-phenylbut-3-enyl)anthracene-9,10-diones as novel shikonin analogs and evaluation of their antiproliferative activities

Por Zhao, Li-Ming, Cao, Feng-Xia, Jin, Hai-Shan, Zhang, Jie-Huan, Szwaya, Jeffrey, Wang, Guangdi
Publicado no Bioorg Med Chem Lett (2016)

Metabolism, pharmacokinetics, and bioavailability of ZB716, a Steroidal Selective Estrogen Receptor Downregulator (SERD)

Por Zhang, Changde, Guo, Shanchun, Yang, Lin, Liu, Jiawang, Zheng, Shilong, Zhong, Qiu, Zhang, Qiang, Wang, Guangdi
Publicado no Oncotarget (2017)

Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations

Por Vue, Bao, Zhang, Sheng, Zhang, Xiaojie, Parisis, Konstantinos, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Publicado no Eur J Med Chem (2015)