Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A

por Velázquez-Moctezuma, Rodrigo, Law, Mansun, Bukh, Jens, Prentoe, Jannick
Publicado en PLoS Pathog (2017)

Hepatitis C Virus Escape Studies of Human Antibody AR3A Reveal a High Barrier to Resistance and Novel Insights on Viral Antibody Evasion Mechanisms

por Velázquez-Moctezuma, Rodrigo, Galli, Andrea, Law, Mansun, Bukh, Jens, Prentoe, Jannick
Publicado en J Virol (2019)

Hepatitis C Virus–Escape Studies for Human Monoclonal Antibody AR4A Reveal Isolate-Specific Resistance and a High Barrier to Resistance

por Velázquez-Moctezuma, Rodrigo, Galli, Andrea, Law, Mansun, Bukh, Jens, Prentoe, Jannick
Publicado en J Infect Dis (2019)

Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity

por Prentoe, Jannick, Velázquez-Moctezuma, Rodrigo, Foung, Steven K. H., Law, Mansun, Bukh, Jens
Publicado en Hepatology (2016)

Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations

por Prentoe, Jannick, Velázquez-Moctezuma, Rodrigo, Augestad, Elias H., Galli, Andrea, Wang, Richard, Law, Mansun, Alter, Harvey, Bukh, Jens
Publicado en Proc Natl Acad Sci U S A (2019)

HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice

por Prentoe, Jannick, Verhoye, Lieven, Velázquez Moctezuma, Rodrigo, Buysschaert, Caroline, Farhoudi, Ali, Wang, Richard, Alter, Harvey, Meuleman, Philip, Bukh, Jens
Publicado en Gut (2016)

Mechanisms of Hepatitis C Virus Escape from Vaccine-Relevant Neutralizing Antibodies

por Velázquez-Moctezuma, Rodrigo, Augestad, Elias H., Castelli, Matteo, Holmboe Olesen, Christina, Clementi, Nicola, Clementi, Massimo, Mancini, Nicasio, Prentoe, Jannick
Publicado en Vaccines (Basel) (2021)

Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens

por Prentoe, Jannick, Janitzek, Christoph M., Velázquez-Moctezuma, Rodrigo, Goksøyr, Louise, Olsen, Rebecca W., Fanalista, Margherita, Augestad, Elias H., Thrane, Susan, Pihl, Anne F., Gottwein, Judith M., Sander, Adam F., Bukh, Jens
Publicado en PLoS One (2021)

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

por Tzarum, Netanel, Giang, Erick, Kadam, Rameshwar U., Chen, Fang, Nagy, Kenna, Augestad, Elias H., Velázquez-Moctezuma, Rodrigo, Keck, Zhen-Yong, Hua, Yuanzi, Stanfield, Robyn L., Dreux, Marlene, Prentoe, Jannick, Foung, Steven K. H., Bukh, Jens, Wilson, Ian A., Law, Mansun
Publicado en Sci Adv (2020)

Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

por Keck, Zhen-Yong, Pierce, Brian G., Lau, Patrick, Lu, Janine, Wang, Yong, Underwood, Alexander, Bull, Rowena A., Prentoe, Jannick, Velázquez-Moctezuma, Rodrigo, Walker, Melanie R., Luciani, Fabio, Guest, Johnathan D., Fauvelle, Catherine, Baumert, Thomas F., Bukh, Jens, Lloyd, Andrew R., Foung, Steven K. H.
Publicado en PLoS Pathog (2019)

Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with hepatitis C virus envelope glycoproteins

por Chen, Fang, Tzarum, Netanel, Lin, Xiaohe, Giang, Erick, Velázquez-Moctezuma, Rodrigo, Augestad, Elias H., Nagy, Kenna, He, Linling, Hernandez, Mayda, Fouch, Mallorie E., Escuer, Ariadna Grinyó i, Chavez, Deborah, Doranz, Benjamin J., Prentoe, Jannick, Stanfield, Robyn L., Lanford, Robert, Bukh, Jens, Wilson, Ian A., Zhu, Jiang, Law, Mansun
Publicado en Immunity (2021)