mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

Por Shackelford, David B., Vasquez, Debbie S., Corbeil, Jacqueline, Wu, Shulin, Leblanc, Mathias, Wu, Chin-Lee, Vera, David R., Shaw, Reuben J.
Publicado em 2009

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Por Gwinn, Dana M., Shackelford, David B., Egan, Daniel F., Mihaylova, Maria M., Mery, Annabelle, Vasquez, Debbie S., Turk, Benjamin E., Shaw, Reuben J.
Publicado em 2008

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Por Shaw, Reuben J., Lamia, Katja A., Vasquez, Debbie, Koo, Seung-Hoi, Bardeesy, Nabeel, DePinho, Ronald A., Montminy, Marc, Cantley, Lewis C.
Publicado em 2005

Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice

Por McClatchy, Daniel B., Ma, Yuanhui, Liu, Chao, Stein, Benjamin D., Martínez-Bartolomé, Salvador, Vasquez, Debbie, Hellberg, Kristina, Shaw, Reuben J., Yates, John R.
Publicado no J Proteome Res (2015)

Class IIa Histone Deacetylases are Hormone-activated regulators of FOXO and Mammalian Glucose Homeostasis

Por Mihaylova, Maria M., Vasquez, Debbie S., Ravnskjaer, Kim, Denechaud, Pierre-Damien, Yu, Ruth T., Alvarez, Jacqueline G., Downes, Michael, Evans, Ronald M., Montminy, Marc, Shaw, Reuben J.
Publicado em 2011

LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin

Por Shackelford, David B., Abt, Evan, Gerken, Laurie, Vasquez, Debbie S., Seki, Atsuko, Leblanc, Mathias, Wei, Liu, Fishbein, Michael C., Czernin, Johannes, Mischel, Paul S., Shaw, Reuben J.
Publicado em 2013

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

Por Lamia, Katja A., Sachdeva, Uma M., DiTacchio, Luciano, Williams, Elliot C., Alvarez, Jacqueline G., Egan, Daniel F., Vasquez, Debbie S., Juguilon, Henry, Panda, Satchidananda, Shaw, Reuben J., Thompson, Craig B., Evans, Ronald M.
Publicado em 2009

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

Por Egan, Daniel F., Shackelford, David B., Mihaylova, Maria M., Gelino, Sara R., Kohnz, Rebecca A., Mair, William, Vasquez, Debbie S., Joshi, Aashish, Gwinn, Dana M., Taylor, Rebecca, Asara, John M., Fitzpatrick, James, Dillin, Andrew, Viollet, Benoit, Kundu, Mondira, Hansen, Malene, Shaw, Reuben J.
Publicado em 2010