Insights into the pathophysiology and therapy of myeloproliferative neoplasms from mouse models

Por Van Etten, R A
Publicado no Leukemia Suppl (2014)

The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products.

Por Wen, S T, Jackson, P K, Van Etten, R A
Publicado em 1996

Blast crisis in a murine model of chronic myelogenous leukemia.

Por Daley, G Q, Van Etten, R A, Baltimore, D
Publicado em 1991

v-abl causes hematopoietic disease distinct from that caused by bcr-abl.

Por Scott, M L, Van Etten, R A, Daley, G Q, Baltimore, D
Publicado em 1991

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.

Por Mayer, B J, Jackson, P K, Van Etten, R A, Baltimore, D
Publicado em 1992

Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.

Por Daley, G Q, Van Etten, R A, Jackson, P K, Bernards, A, Baltimore, D
Publicado em 1992

Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.

Por Wetzler, M, Talpaz, M, Van Etten, R A, Hirsh-Ginsberg, C, Beran, M, Kurzrock, R
Publicado em 1993

Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin.

Por Wetzler, M, Talpaz, M, Yee, G, Stass, S A, Van Etten, R A, Andreeff, M, Goodacre, A M, Kleine, H D, Mahadevia, R K, Kurzrock, R
Publicado em 1995

Childhood leukemia: electric and magnetic fields as possible risk factors.

Por Brain, Joseph D, Kavet, Robert, McCormick, David L, Poole, Charles, Silverman, Lewis B, Smith, Thomas J, Valberg, Peter A, Van Etten, R A, Weaver, James C
Publicado em 2003

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2...

Por Schwaller, J, Frantsve, J, Aster, J, Williams, I R, Tomasson, M H, Ross, T S, Peeters, P, Van Rompaey, L, Van Etten, R A, Ilaria, R, Marynen, P, Gilliland, D G
Publicado em 1998