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Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.

N-terminal myristoylation can promote the association of proteins with the plasma membrane, a property that is required for oncogenic variants of Src and Abl to transform fibroblastic cell types. The P210bcr/abl protein of chronic myelogenous leukemia cells is not myristoylated and does not stably t...

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Detalhes bibliográficos
Main Authors: Daley, G Q, Van Etten, R A, Jackson, P K, Bernards, A, Baltimore, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369630/
https://ncbi.nlm.nih.gov/pubmed/1549131
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