Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin.

The disruption of the BCR gene and its juxtaposition to and consequent activation of the ABL gene has been implicated as the critical molecular defect in Philadelphia chromosome-positive leukemias. The normal BCR protein is a multifunctional molecule with domains that suggest its participation in ph...

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Bibliographic Details
Main Authors: Wetzler, M, Talpaz, M, Yee, G, Stass, S A, Van Etten, R A, Andreeff, M, Goodacre, A M, Kleine, H D, Mahadevia, R K, Kurzrock, R
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42192/
https://ncbi.nlm.nih.gov/pubmed/7724587
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