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Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin.

The disruption of the BCR gene and its juxtaposition to and consequent activation of the ABL gene has been implicated as the critical molecular defect in Philadelphia chromosome-positive leukemias. The normal BCR protein is a multifunctional molecule with domains that suggest its participation in ph...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wetzler, M, Talpaz, M, Yee, G, Stass, S A, Van Etten, R A, Andreeff, M, Goodacre, A M, Kleine, H D, Mahadevia, R K, Kurzrock, R
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3488
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