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Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin.

The disruption of the BCR gene and its juxtaposition to and consequent activation of the ABL gene has been implicated as the critical molecular defect in Philadelphia chromosome-positive leukemias. The normal BCR protein is a multifunctional molecule with domains that suggest its participation in ph...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wetzler, M, Talpaz, M, Yee, G, Stass, S A, Van Etten, R A, Andreeff, M, Goodacre, A M, Kleine, H D, Mahadevia, R K, Kurzrock, R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3488
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