Ultra-multiplexed analysis of single-cell dynamics reveals logic rules in differentiation

por Zhang, Ce, Tu, Hsiung-Lin, Jia, Gengjie, Mukhtar, Tanzila, Taylor, Verdon, Rzhetsky, Andrey, Tay, Savaş
Publicado en Sci Adv (2019)

Monitoring the Waiting Time Sequence of Single Ras GTPase Activation Events Using Liposome Functionalized Zero-Mode Waveguides

por Christensen, Sune M., Triplet, Meredith G., Rhodes, Christopher, Iwig, Jeffrey S., Tu, Hsiung-Lin, Stamou, Dimitrios, Groves, Jay T.
Publicado en Nano Lett (2016)

Ultra-sensitive digital quantification of proteins and mRNA in single cells

por Lin, Jing, Jordi, Christian, Son, Minjun, Van Phan, Hoang, Drayman, Nir, Abasiyanik, Mustafa Fatih, Vistain, Luke, Tu, Hsiung-Lin, Tay, Savaş
Publicado en Nat Commun (2019)

NF-κB responds to absolute differences in cytokine concentrations

por Son, Minjun, Wang, Andrew G., Tu, Hsiung-Lin, Metzig, Marie Oliver, Patel, Parthiv, Husain, Kabir, Lin, Jing, Murugan, Arvind, Hoffmann, Alexander, Tay, Savaş
Publicado en Sci Signal (2021)

H-Ras forms dimers on membrane surfaces via a protein–protein interface

por Lin, Wan-Chen, Iversen, Lars, Tu, Hsiung-Lin, Rhodes, Christopher, Christensen, Sune M., Iwig, Jeffrey S., Hansen, Scott D., Huang, William Y. C., Groves, Jay T.
Publicado 2014

Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS

por Huang, William Y. C., Yan, Qingrong, Lin, Wan-Chen, Chung, Jean K., Hansen, Scott D., Christensen, Sune M., Tu, Hsiung-Lin, Kuriyan, John, Groves, Jay T.
Publicado en Proc Natl Acad Sci U S A (2016)

One-way membrane trafficking of SOS in receptor-triggered Ras activation

por Christensen, Sune M., Tu, Hsiung-Lin, Jun, Jesse E., Alvarez, Steven, Triplet, Meredith G., Iwig, Jeffrey S., Yadav, Kamlesh K., Bar-Sagi, Dafna, Roose, Jeroen P., Groves, Jay T.
Publicado en Nat Struct Mol Biol (2016)

Construction of intracellular asymmetry and asymmetric division in Escherichia coli

por Lin, Da-Wei, Liu, Yang, Lee, Yue-Qi, Yang, Po-Jiun, Ho, Chia-Tse, Hong, Jui-Chung, Hsiao, Jye-Chian, Liao, Der-Chien, Liang, An-Jou, Hung, Tzu-Chiao, Chen, Yu-Chuan, Tu, Hsiung-Lin, Hsu, Chao-Ping, Huang, Hsiao-Chun
Publicado en Nat Commun (2021)

Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics

por Iversen, Lars, Tu, Hsiung-Lin, Lin, Wan-Chen, Christensen, Sune M., Abel, Steven M., Iwig, Jeff, Wu, Hung-Jen, Gureasko, Jodi, Rhodes, Christopher, Petit, Rebecca S., Hansen, Scott D., Thill, Peter, Yu, Cheng-Han, Stamou, Dimitrios, Chakraborty, Arup K., Kuriyan, John, Groves, Jay T.
Publicado en Science (2014)