Ultra-sensitive digital quantification of proteins and mRNA in single cells

Simultaneous measurement of proteins and mRNA in single cells enables quantitative understanding and modeling of cellular functions. Here, we present an automated microfluidic system for multi-parameter and ultra-sensitive protein/mRNA measurements in single cells. Our technology improves the sensit...

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Publicat a:Nat Commun
Autors principals: Lin, Jing, Jordi, Christian, Son, Minjun, Van Phan, Hoang, Drayman, Nir, Abasiyanik, Mustafa Fatih, Vistain, Luke, Tu, Hsiung-Lin, Tay, Savaş
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685952/
https://ncbi.nlm.nih.gov/pubmed/31391463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11531-z
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