Ultra-sensitive digital quantification of proteins and mRNA in single cells

Simultaneous measurement of proteins and mRNA in single cells enables quantitative understanding and modeling of cellular functions. Here, we present an automated microfluidic system for multi-parameter and ultra-sensitive protein/mRNA measurements in single cells. Our technology improves the sensit...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Lin, Jing, Jordi, Christian, Son, Minjun, Van Phan, Hoang, Drayman, Nir, Abasiyanik, Mustafa Fatih, Vistain, Luke, Tu, Hsiung-Lin, Tay, Savaş
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685952/
https://ncbi.nlm.nih.gov/pubmed/31391463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11531-z
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