A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes

Por Tran, Timothy H., Krishnamoorthy, Kalyanaraman, Begley, Tadhg P., Ealick, Steven E.
Publicado em 2011

The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases()

Por Tran, Timothy H., Christoffersen, S., Allan, Paula W., Parker, William B., Piskur, Jure, Serra, I., Terreni, M., Ealick, Steven E.
Publicado em 2011

Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase

Por Tran, Timothy H., Hsiao, Yu-Shan, Jo, Jeanyoung, Chou, Chi-Yuan, Dietrich, Lars E.P., Walz, Thomas, Tong, Liang
Publicado no Nature (2014)

Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

Por Dharmaiah, Srisathiyanarayanan, Bindu, Lakshman, Tran, Timothy H., Gillette, William K., Frank, Peter H., Ghirlando, Rodolfo, Nissley, Dwight V., Esposito, Dominic, McCormick, Frank, Stephen, Andrew G., Simanshu, Dhirendra K.
Publicado no Proc Natl Acad Sci U S A (2016)

Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates

Por Katz, Francine S., Pecic, Stevan, Tran, Timothy H., Trakht, Ilya, Schneider, Laura, Zhu, Zhengxiang, Ton-That, Long, Luzac, Michal, Zlatanic, Viktor, Damera, Shivani, Macdonald, Joanne, Landry, Donald W., Tong, Liang, Stojanovic, Milan N.
Publicado no Chembiochem (2015)

Multivalent small molecule pan-RAS inhibitors

Por Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Publicado no Cell (2017)

Crystal Structures of Malonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations

Por Froese, D. Sean, Forouhar, Farhad, Tran, Timothy H., Vollmar, Melanie, Kim, Yi Seul, Lew, Scott, Neely, Helen, Seetharaman, Jayaraman, Shen, Yang, Xiao, Rong, Acton, Thomas B., Everett, John K., Cannone, Giuseppe, Puranik, Sriharsha, Savitsky, Pavel, Krojer, Tobias, Pilka, Ewa S., Kiyani, Wasim, Lee, Wen Hwa, Marsden, Brian D., von Delft, Frank, Allerston, Charles K., Spagnolo, Laura, Gileadi, Opher, Montelione, Gaetano T., Oppermann, Udo, Yue, Wyatt W., Tong, Liang
Publicado em 2013