Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy

Por Caillet-Boudin, Marie-Laure, Fernandez-Gomez, Francisco-Jose, Tran, Hélène, Dhaenens, Claire-Marie, Buee, Luc, Sergeant, Nicolas
Publicado em 2014

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons

Por Lopez-Gonzalez, Rodrigo, Lu, Yubing, Gendron, Tania F., Karydas, Anna, Tran, Helene, Yang, Dejun, Petrucelli, Leonard, Miller, Bruce L., Almeida, Sandra, Gao, Fen-Biao
Publicado no Neuron (2016)

Differential Toxicity of Nuclear RNA Foci Versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

Por Tran, Helene, Almeida, Sandra, Moore, Jill, Gendron, Tania F., Chalasani, UmaDevi, Lu, Yubing, Du, Xing, Nickerson, Jeffrey A., Petrucelli, Leonard, Weng, Zhiping, Gao, Fen-Biao
Publicado no Neuron (2015)

Consensus Brain-derived Protein, Extraction Protocol for the Study of Human and Murine Brain Proteome Using Both 2D-DIGE and Mini 2DE Immunoblotting

Por Fernandez-Gomez, Francisco-Jose, Jumeau, Fanny, Derisbourg, Maxime, Burnouf, Sylvie, Tran, Hélène, Eddarkaoui, Sabiha, Obriot, Hélène, Dutoit-Lefevre, Virginie, Deramecourt, Vincent, Mitchell, Valérie, Lefranc, Didier, Hamdane, Malika, Blum, David, Buée, Luc, Buée-Scherrer, Valérie, Sergeant, Nicolas
Publicado em 2014

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

Por Almeida, Sandra, Gascon, Eduardo, Tran, Hélène, Chou, Hsin Jung, Gendron, Tania F., DeGroot, Steven, Tapper, Andrew R., Sellier, Chantal, Charlet-Berguerand, Nicolas, Karydas, Anna, Seeley, William W., Boxer, Adam L., Petrucelli, Leonard, Miller, Bruce L., Gao, Fen-Biao
Publicado em 2013

Erratum to: Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

Por Almeida, Sandra, Gascon, Eduardo, Tran, Hélène, Chou, Hsin Jung, Gendron, Tania F., DeGroot, Steven, Tapper, Andrew R., Sellier, Chantal, Charlet-Berguerand, Nicolas, Karydas, Anna, Seeley, William W., Boxer, Adam L., Petrucelli, Leonard, Miller, Bruce L., Gao, Fen-Biao
Publicado no Acta Neuropathol (2014)

Analysis of Exonic Regions Involved in Nuclear Localization, Splicing Activity, and Dimerization of Muscleblind-like-1 Isoforms

Por Tran, Hélène, Gourrier, Nathalie, Lemercier-Neuillet, Camille, Dhaenens, Claire-Marie, Vautrin, Audrey, Fernandez-Gomez, Francisco José, Arandel, Ludovic, Carpentier, Céline, Obriot, Hélène, Eddarkaoui, Sabiha, Delattre, Lucie, Van Brussels, Edwige, Holt, Ian, Morris, Glenn E., Sablonnière, Bernard, Buée, Luc, Charlet-Berguerand, Nicolas, Schraen-Maschke, Susanna, Furling, Denis, Behm-Ansmant, Isabelle, Branlant, Christiane, Caillet-Boudin, Marie-Laure, Sergeant, Nicolas
Publicado em 2011

Expression of human C9ORF72 hexanucleotide expansion reproduces RNA foci and dipeptide repeat proteins but not neurodegeneration in BAC transgenic mice

Por Peters, Owen M., Cabrera, Gabriela Toro, Tran, Helene, Gendron, Tania F., McKeon, Jeanne E., Metterville, Jake, Weiss, Alexandra, Wightman, Nicholas, Salameh, Johnny, Kim, Juyhun, Sun, Huaming, Boylan, Kevin B., Dickson, Dennis, Kennedy, Zack, Lin, Ziqiang, Zhang, Yong-Jie, Daughrity, Lillian, Jung, Chris, Gao, Fen-Biao, Sapp, Peter C., Horvitz, H Robert, Bosco, Daryl A., Brown, Solange P., de Jong, Pieter, Petrucelli, Leonard, Mueller, Chris, Brown, Robert H.
Publicado no Neuron (2015)