Nano-LC-MS/MS for Quantification of Lyso-Gb3 and Its Analogues Reveals a Useful Biomarker for Fabry Disease

Por Sueoka, Hideaki, Ichihara, Junji, Tsukimura, Takahiro, Togawa, Tadayasu, Sakuraba, Hitoshi
Publicado no PLoS One (2015)

Distributions of Globotriaosylceramide Isoforms, and Globotriaosylsphingosine and Its Analogues in an α-Galactosidase A Knockout Mouse, a Model of Fabry Disease

Por Sueoka, Hideaki, Aoki, Mikio, Tsukimura, Takahiro, Togawa, Tadayasu, Sakuraba, Hitoshi
Publicado no PLoS One (2015)

Clinical and biochemical investigation of male patients exhibiting membranous cytoplasmic bodies in biopsied kidney tissues; a pitfall in diagnosis of Fabry disease

Por Sakuraba, Hitoshi, Tsukimura, Takahiro, Tanaka, Toshie, Togawa, Tadayasu, Takahashi, Naoki, Mikami, Daisuke, Wakai, Sachiko, Akai, Yasuhiro
Publicado no J Nephropathol (2015)

Plasma mutant α-galactosidase A protein and globotriaosylsphingosine level in Fabry disease

Por Tsukimura, Takahiro, Nakano, Sachie, Togawa, Tadayasu, Tanaka, Toshie, Saito, Seiji, Ohno, Kazuki, Shibasaki, Futoshi, Sakuraba, Hitoshi
Publicado no Mol Genet Metab Rep (2014)

Impaired Neural Differentiation of Induced Pluripotent Stem Cells Generated from a Mouse Model of Sandhoff Disease

Por Ogawa, Yasuhiro, Tanaka, Makoto, Tanabe, Miho, Suzuki, Toshihiro, Togawa, Tadayasu, Fukushige, Tomoko, Kanekura, Takuro, Sakuraba, Hitoshi, Oishi, Kazuhiko
Publicado em 2013

Development of a Highly Sensitive Immuno-PCR Assay for the Measurement of α-Galactosidase A Protein Levels in Serum and Plasma

Por Nakano, Sachie, Morizane, Yoshihito, Makisaka, Noriko, Suzuki, Toshihiro, Togawa, Tadayasu, Tsukimura, Takahiro, Kawashima, Ikuo, Sakuraba, Hitoshi, Shibasaki, Futoshi
Publicado em 2013

Efficient Uptake of Recombinant α-Galactosidase A Produced with a Gene-Manipulated Yeast by Fabry Mice Kidneys

Por Tsukimura, Takahiro, Kawashima, Ikuo, Togawa, Tadayasu, Kodama, Takashi, Suzuki, Toshihiro, Watanabe, Toru, Chiba, Yasunori, Jigami, Yoshifumi, Fukushige, Tomoko, Kanekura, Takuro, Sakuraba, Hitoshi
Publicado em 2011

Lyso-GM2 Ganglioside: A Possible Biomarker of Tay-Sachs Disease and Sandhoff Disease

Por Kodama, Takashi, Togawa, Tadayasu, Tsukimura, Takahiro, Kawashima, Ikuo, Matsuoka, Kazuhiko, Kitakaze, Keisuke, Tsuji, Daisuke, Itoh, Kohji, Ishida, Yo-ichi, Suzuki, Minoru, Suzuki, Toshihiro, Sakuraba, Hitoshi
Publicado em 2011

Rapid Immunochromatographic Detection of Serum Anti-α-Galactosidase A Antibodies in Fabry Patients after Enzyme Replacement Therapy

Por Nakano, Sachie, Tsukimura, Takahiro, Togawa, Tadayasu, Ohashi, Toya, Kobayashi, Masahisa, Takayama, Katsuyoshi, Kobayashi, Yukuharu, Abiko, Hiroshi, Satou, Masatsugu, Nakahata, Tohru, Warnock, David G., Sakuraba, Hitoshi, Shibasaki, Futoshi
Publicado no PLoS One (2015)

FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice

Por Ogawa, Yasuhiro, Sano, Takafumi, Irisa, Masahiro, Kodama, Takashi, Saito, Takahiro, Furusawa, Eiri, Kaizu, Katsutoshi, Yanagi, Yusuke, Tsukimura, Takahiro, Togawa, Tadayasu, Yamanaka, Shoji, Itoh, Kohji, Sakuraba, Hitoshi, Oishi, Kazuhiko
Publicado no Sci Rep (2017)

Use of a Modified α-N-Acetylgalactosaminidase in the Development of Enzyme Replacement Therapy for Fabry Disease

Por Tajima, Youichi, Kawashima, Ikuo, Tsukimura, Takahiro, Sugawara, Kanako, Kuroda, Mayuko, Suzuki, Toshihiro, Togawa, Tadayasu, Chiba, Yasunori, Jigami, Yoshifumi, Ohno, Kazuki, Fukushige, Tomoko, Kanekura, Takuro, Itoh, Kohji, Ohashi, Toya, Sakuraba, Hitoshi
Publicado em 2009

Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model

Por Kitakaze, Keisuke, Mizutani, Yasumichi, Sugiyama, Eiji, Tasaki, Chikako, Tsuji, Daisuke, Maita, Nobuo, Hirokawa, Takatsugu, Asanuma, Daisuke, Kamiya, Mako, Sato, Kohei, Setou, Mitsutoshi, Urano, Yasuteru, Togawa, Tadayasu, Otaka, Akira, Sakuraba, Hitoshi, Itoh, Kohji
Publicado no J Clin Invest (2016)