Enhancement by Uridine Diphosphate of Macrophage Inflammatory Protein-1 Alpha Production in Microglia Derived from Sandhoff Disease Model Mice

Por Kawashita, Eri, Tsuji, Daisuke, Kanno, Yosuke, Tsuchida, Kaho, Itoh, Kohji
Publicado no JIMD Rep (2015)

Prostaglandin E2 Reverses Aberrant Production of an Inflammatory Chemokine by Microglia from Sandhoff Disease Model Mice through the cAMP-PKA Pathway

Por Kawashita, Eri, Tsuji, Daisuke, Toyoshima, Masahiro, Kanno, Yosuke, Matsuno, Hiroyuki, Itoh, Kohji
Publicado em 2011

Introduction of an N-Glycan Sequon Into HEXA Enhances Human β-Hexosaminidase Cellular Uptake in a Model of Sandhoff Disease

Por Matsuoka, Kazuhiko, Tsuji, Daisuke, Aikawa, Sei-ichi, Matsuzawa, Fumiko, Sakuraba, Hitoshi, Itoh, Kohji
Publicado em 2010

Proteomic alteration in gastic adenocarcinomas from Japanese patients

Por Yoshihara, Takahiro, Kadota, Yoshito, Yoshimura, Yoshiyuki, Tatano, Yutaka, Takeuchi, Naohiro, Okitsu, Hiroshi, Umemoto, Atsushi, Yamauchi, Takashi, Itoh, Kohji
Publicado em 2006

Therapeutic Potential of Intracerebroventricular Replacement of Modified Human β-Hexosaminidase B for GM2 Gangliosidosis

Por Matsuoka, Kazuhiko, Tamura, Tomomi, Tsuji, Daisuke, Dohzono, Yukie, Kitakaze, Keisuke, Ohno, Kazuki, Saito, Seiji, Sakuraba, Hitoshi, Itoh, Kohji
Publicado em 2011

Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System

Por Tsuda, Yusuke, Shigenaga, Akira, Tsuji, Kohei, Denda, Masaya, Sato, Kohei, Kitakaze, Keisuke, Nakamura, Takahiro, Inokuma, Tsubasa, Itoh, Kohji, Otaka, Akira
Publicado no ChemistryOpen (2015)

Production of Recombinant β-Hexosaminidase A, a Potential Enzyme for Replacement Therapy for Tay-Sachs and Sandhoff Diseases, in the Methylotrophic Yeast Ogataea minuta

Por Akeboshi, Hiromi, Chiba, Yasunori, Kasahara, Yoshiko, Takashiba, Minako, Takaoka, Yuki, Ohsawa, Mai, Tajima, Youichi, Kawashima, Ikuo, Tsuji, Daisuke, Itoh, Kohji, Sakuraba, Hitoshi, Jigami, Yoshifumi
Publicado em 2007

Lyso-GM2 Ganglioside: A Possible Biomarker of Tay-Sachs Disease and Sandhoff Disease

Por Kodama, Takashi, Togawa, Tadayasu, Tsukimura, Takahiro, Kawashima, Ikuo, Matsuoka, Kazuhiko, Kitakaze, Keisuke, Tsuji, Daisuke, Itoh, Kohji, Ishida, Yo-ichi, Suzuki, Minoru, Suzuki, Toshihiro, Sakuraba, Hitoshi
Publicado em 2011

Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation

Por Hanson, Derek James, Nakamura, Shingen, Amachi, Ryota, Hiasa, Masahiro, Oda, Asuka, Tsuji, Daisuke, Itoh, Kohji, Harada, Takeshi, Horikawa, Kazuki, Teramachi, Jumpei, Miki, Hirokazu, Matsumoto, Toshio, Abe, Masahiro
Publicado no Oncotarget (2015)

FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice

Por Ogawa, Yasuhiro, Sano, Takafumi, Irisa, Masahiro, Kodama, Takashi, Saito, Takahiro, Furusawa, Eiri, Kaizu, Katsutoshi, Yanagi, Yusuke, Tsukimura, Takahiro, Togawa, Tadayasu, Yamanaka, Shoji, Itoh, Kohji, Sakuraba, Hitoshi, Oishi, Kazuhiko
Publicado no Sci Rep (2017)

Use of a Modified α-N-Acetylgalactosaminidase in the Development of Enzyme Replacement Therapy for Fabry Disease

Por Tajima, Youichi, Kawashima, Ikuo, Tsukimura, Takahiro, Sugawara, Kanako, Kuroda, Mayuko, Suzuki, Toshihiro, Togawa, Tadayasu, Chiba, Yasunori, Jigami, Yoshifumi, Ohno, Kazuki, Fukushige, Tomoko, Kanekura, Takuro, Itoh, Kohji, Ohashi, Toya, Sakuraba, Hitoshi
Publicado em 2009

Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model

Por Kitakaze, Keisuke, Mizutani, Yasumichi, Sugiyama, Eiji, Tasaki, Chikako, Tsuji, Daisuke, Maita, Nobuo, Hirokawa, Takatsugu, Asanuma, Daisuke, Kamiya, Mako, Sato, Kohei, Setou, Mitsutoshi, Urano, Yasuteru, Togawa, Tadayasu, Otaka, Akira, Sakuraba, Hitoshi, Itoh, Kohji
Publicado no J Clin Invest (2016)

Combination with a Defucosylated Anti-HM1.24 Monoclonal Antibody plus Lenalidomide Induces Marked ADCC against Myeloma Cells and Their Progenitors

Por Harada, Takeshi, Ozaki, Shuji, Oda, Asuka, Tsuji, Daisuke, Ikegame, Akishige, Iwasa, Masami, Udaka, Kengo, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Kagawa, Kumiko, Kuroda, Yoshiaki, Kawai, Shigeto, Itoh, Kohji, Yamada-Okabe, Hisafumi, Matsumoto, Toshio, Abe, Masahiro
Publicado em 2013

Glycolysis Inhibition Inactivates ABC Transporters to Restore Drug Sensitivity in Malignant Cells

Por Nakano, Ayako, Tsuji, Daisuke, Miki, Hirokazu, Cui, Qu, Sayed, Salah Mohamed El, Ikegame, Akishige, Oda, Asuka, Amou, Hiroe, Nakamura, Shingen, Harada, Takeshi, Fujii, Shiro, Kagawa, Kumiko, Takeuchi, Kyoko, Sakai, Akira, Ozaki, Shuji, Okano, Kazuma, Nakamura, Takahiro, Itoh, Kohji, Matsumoto, Toshio, Abe, Masahiro
Publicado em 2011

In vivo crystallography at X-ray free-electron lasers: the next generation of structural biology?

Por Gallat, François-Xavier, Matsugaki, Naohiro, Coussens, Nathan P., Yagi, Koichiro J., Boudes, Marion, Higashi, Tetsuya, Tsuji, Daisuke, Tatano, Yutaka, Suzuki, Mamoru, Mizohata, Eiichi, Tono, Kensuke, Joti, Yasumasa, Kameshima, Takashi, Park, Jaehyun, Song, Changyong, Hatsui, Takaki, Yabashi, Makina, Nango, Eriko, Itoh, Kohji, Coulibaly, Fasséli, Tobe, Stephen, Ramaswamy, S., Stay, Barbara, Iwata, So, Chavas, Leonard M. G.
Publicado em 2014