Stabilization of Nucleotide Binding Domain Dimers Rescues ABCC6 Mutants Associated with Pseudoxanthoma Elasticum

Por Ran, Yanchao, Thibodeau, Patrick H.
Publicado no J Biol Chem (2017)

Calcium-induced Folding and Stabilization of the Pseudomonas aeruginosa Alkaline Protease

Por Zhang, Liang, Conway, James F., Thibodeau, Patrick H.
Publicado em 2012

Regulation of ABCC6 Trafficking and Stability by a Conserved C-terminal PDZ-Like Sequence

Por Xue, Peng, Crum, Chelsea M., Thibodeau, Patrick H.
Publicado em 2014

Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens

Por Zhang, Liang, Morrison, Anneliese J., Thibodeau, Patrick H.
Publicado no PLoS One (2015)

Side chain and backbone contributions of Phe508 to CFTR folding

Por Thibodeau, Patrick H, Brautigam, Chad A, Machius, Mischa, Thomas, Philip J
Publicado em 2004

Modulation of the Epithelial Sodium Channel (ENaC) by Bacterial Metalloproteases and Protease Inhibitors

Por Butterworth, Michael B., Zhang, Liang, Liu, Xiaoning, Shanks, Robert M., Thibodeau, Patrick H.
Publicado em 2014

Inducible Polymerization and Two-Dimensional Assembly of the Repeats-in-Toxin (RTX) Domain from the Pseudomonas aeruginosa Alkaline Protease

Por Zhang, Liang, Franks, Jonathon, Stolz, Donna B., Conway, James F., Thibodeau, Patrick H.
Publicado em 2014

ESCRT-dependent targeting of plasma membrane localized KCa3.1 to the lysosomes

Por Balut, Corina M., Gao, Yajuan, Murray, Sandra A., Thibodeau, Patrick H., Devor, Daniel C.
Publicado em 2010

Activation of the Epithelial Sodium Channel (ENaC) by the Alkaline Protease from Pseudomonas aeruginosa

Por Butterworth, Michael B., Zhang, Liang, Heidrich, Elisa M., Myerburg, Michael M., Thibodeau, Patrick H.
Publicado em 2012

Mutations in the yeast Hsp70, Ssa1, at P417 alter ATP cycling, interdomain coupling, and specific chaperone functions

Por Needham, Patrick G, Patel, Hardik J., Chiosis, Gabriela, Thibodeau, Patrick H., Brodsky, Jeffrey L.
Publicado no J Mol Biol (2015)

NMR evidence for differential phosphorylation-dependent interactions in WT and ΔF508 CFTR

Por Kanelis, Voula, Hudson, Rhea P, Thibodeau, Patrick H, Thomas, Philip J, Forman-Kay, Julie D
Publicado em 2010

Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation

Por Gong, Xiaoyan, Ahner, Annette, Roldan, Ariel, Lukacs, Gergely L., Thibodeau, Patrick H., Frizzell, Raymond A.
Publicado no J Biol Chem (2016)

Identification of SlpB, a Cytotoxic Protease from Serratia marcescens

Por Shanks, Robert M. Q., Stella, Nicholas A., Hunt, Kristin M., Brothers, Kimberly M., Zhang, Liang, Thibodeau, Patrick H.
Publicado no Infect Immun (2015)

Revertant mutants modify, but do not rescue, the gating defect of the cystic fibrosis mutant G551D-CFTR

Por Xu, Zhe, Pissarra, Luísa S, Farinha, Carlos M, Liu, Jia, Cai, Zhiwei, Thibodeau, Patrick H, Amaral, Margarida D, Sheppard, David N
Publicado no J Physiol (2014)

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway

Por Ahner, Annette, Gong, Xiaoyan, Schmidt, Bela Z., Peters, Kathryn W., Rabeh, Wael M., Thibodeau, Patrick H., Lukacs, Gergely L., Frizzell, Raymond A.
Publicado em 2013

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

Por Baker, Jennifer M R, Hudson, Rhea P, Kanelis, Voula, Choy, Wing-Yiu, Thibodeau, Patrick H, Thomas, Philip J, Forman-Kay, Julie D
Publicado em 2007

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

Por Thibodeau, Patrick H., Richardson, John M., Wang, Wei, Millen, Linda, Watson, Jarod, Mendoza, Juan L., Du, Kai, Fischman, Sharon, Senderowitz, Hanoch, Lukacs, Gergely L., Kirk, Kevin, Thomas, Philip J.
Publicado em 2010

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

Por Lewis, Hal A, Buchanan, Sean G, Burley, Stephen K, Conners, Kris, Dickey, Mark, Dorwart, Michael, Fowler, Richard, Gao, Xia, Guggino, William B, Hendrickson, Wayne A, Hunt, John F, Kearins, Margaret C, Lorimer, Don, Maloney, Peter C, Post, Kai W, Rajashankar, Kanagalaghatta R, Rutter, Marc E, Sauder, J Michael, Shriver, Stephanie, Thibodeau, Patrick H, Thomas, Philip J, Zhang, Marie, Zhao, Xun, Emtage, Spencer
Publicado em 2004