The Power of Phase I Studies to Detect Clinical Relevant QTc Prolongation: A Resampling Simulation Study

od Ferber, Georg, Lorch, Ulrike, Täubel, Jörg
izdano v Biomed Res Int (2015)

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity

od Ferber, Georg, Fernandes, Sara, Täubel, Jörg
izdano v J Clin Pharmacol (2017)

Stability of the Effect of a Standardized Meal on QTc

od Täubel, Jörg, Fernandes, Sara, Ferber, Georg
izdano v Ann Noninvasive Electrocardiol (2016)

Three steps to writing adaptive study protocols in the early phase clinical development of new medicines

od Lorch, Ulrike, O’Kane, Martin, Taubel, Jorg
Izdano 2014

Burns after photodynamic therapy

od Hettiaratchy, Shehan, Clarke, John, Taubel, Jorg, Besa, Chola
Izdano 2000

Comparison of Digital 12‐Lead ECG and Digital 12‐Lead Holter ECG Recordings in Healthy Male Subjects: Results from a Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial...

od Wang, Duolao, Bakhai, Ameet, Arezina, Radivoj, Täubel, Jörg
izdano v Ann Noninvasive Electrocardiol (2016)

The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers

od Muirhead, Gary J, Faulkner, Stephen, Harness, Jane A, Taubel, Jörg
Izdano 2002

Safety, Tolerability, and Dose Proportionality of a Novel Transdermal Fentanyl Matrix Patch and Bioequivalence With a Matrix Fentanyl Patch: Two Phase 1 Single‐Center Open‐Label, R...

od Lorch, Ulrike, Pierscionek, Tomasz, Freier, Anne, Spencer, Christopher S., Täubel, Jörg
izdano v Clin Pharmacol Drug Dev (2020)

Pharmacokinetics, Safety and Cognitive Function Profile of Rupatadine 10, 20 and 40 mg in Healthy Japanese Subjects: A Randomised Placebo-Controlled Trial

od Täubel, Jörg, Ferber, Georg, Fernandes, Sara, Lorch, Ulrike, Santamaría, Eva, Izquierdo, Iñaki
izdano v PLoS One (2016)

Repeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers

od Taubel, Jorg, Naseem, Asif, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A. John
Izdano 2012

Thorough QT study of the effect of oral moxifloxacin on QT(c) interval in the fed and fasted state in healthy Japanese and Caucasian subjects

od Taubel, Jorg, Ferber, Georg, Lorch, Ulrike, Batchvarov, Velislav, Savelieva, Irina, Camm, A John
Izdano 2014

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising...

od Täubel, Jörg, Ferber, Georg, Lorch, Ulrike, Wang, Duolao, Sust, Mariano, Camm, A. John
izdano v PLoS One (2015)

Thorough QT study of the effect of intravenous amisulpride on QTc interval in Caucasian and Japanese healthy subjects

od Täubel, Jörg, Ferber, Georg, Fox, Gabriel, Fernandes, Sara, Lorch, Ulrike, Camm, A. John
izdano v Br J Clin Pharmacol (2016)

Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first‐in‐human trial in healthy postmenopausal women

od Pohl, Oliver, Marchand, Line, Gotteland, Jean‐Pierre, Coates, Simon, Täubel, Jörg, Lorch, Ulrike
izdano v Br J Clin Pharmacol (2018)

Coadministration of the prostaglandin F2α receptor antagonist preterm labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone

od Pohl, Oliver, Marchand, Line, Gotteland, Jean‐Pierre, Coates, Simon, Täubel, Jörg, Lorch, Ulrike
izdano v Br J Clin Pharmacol (2019)

Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials

od Coates, Simon, Wang, Duolao, Pierscionek, Tomasz, Fernandes, Sara, Djumanov, Dilshat, Lorch, Ulrike, Täubel, Jörg
izdano v Front Pharmacol (2020)

Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers

od Taubel, Jorg, Naseem, Asif, Harada, Tomohiko, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A John
Izdano 2010

Pharmacodynamic Consequences of Administration of VLA-4 Antagonist CDP323 to Multiple Sclerosis Subjects: A Randomized, Double-Blind Phase 1/2 Study

od Wolf, Christian, Sidhu, Jagdev, Otoul, Christian, Morris, Dexter L., Cnops, Jennifer, Taubel, Jorg, Bennett, Barbara
Izdano 2013

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers

od Taubel, Jorg, Lorch, Ulrike, Ferber, Georg, Singh, Jatinder, Batchvarov, Velislav N, Savelieva, Irina, Camm, A John
Izdano 2013

Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects

od Dixon, Ruth, Job, Sarah, Oliver, Ruth, Tompson, Debra, Wright, John G, Maltby, Kay, Lorch, Ulrike, Taubel, Jorg
Izdano 2008