The Role of Rhodopsin Glycosylation in Protein Folding, Trafficking, and Light-Sensitive Retinal Degeneration

by Tam, Beatrice M., Moritz, Orson L.
Published in J Neurosci (2009)

Dark Rearing Rescues P23H Rhodopsin-Induced Retinal Degeneration in a Transgenic Xenopus laevis Model of Retinitis Pigmentosa: A Chromophore-Dependent Mechanism Characterized by Pr...

by Tam, Beatrice M., Moritz, Orson L.
Published in J Neurosci (2007)

The C Terminus of Peripherin/rds Participates in Rod Outer Segment Targeting and Alignment of Disk Incisures

by Tam, Beatrice M., Moritz, Orson L., Papermaster, David S.
Published 2004

Targeting of mouse guanylate cyclase 1 (Gucy2e) to Xenopus laevis rod outer segments

by Karan, Sukanya, Tam, Beatrice M., Moritz, Orson L., Baehr, Wolfgang
Published 2011

An interaction network between the SNARE VAMP7 and Rab GTPases within a ciliary membrane-targeting complex

by Kandachar, Vasundhara, Tam, Beatrice M., Moritz, Orson L., Deretic, Dusanka
Published in J Cell Sci (2018)

Autophagy in Xenopus laevis rod photoreceptors is independently regulated by phototransduction and misfolded RHO(P23H)

by Wen, Runxia H, Stanar, Paloma, Tam, Beatrice, Moritz, Orson L
Published in Autophagy (2019)

Identification of an Outer Segment Targeting Signal in the Cooh Terminus of Rhodopsin Using Transgenic Xenopus laevis

by Tam, Beatrice M., Moritz, Orson L., Hurd, Lawrence B., Papermaster, David S.
Published 2000

Mislocalized Rhodopsin Does Not Require Activation to Cause Retinal Degeneration and Neurite Outgrowth in Xenopus laevis

by Tam, Beatrice M., Xie, Guifu, Oprian, Daniel D., Moritz, Orson L.
Published in J Neurosci (2006)

Photoactivation-Induced Instability of Rhodopsin Mutants T4K and T17M in Rod Outer Segments Underlies Retinal Degeneration in X. laevis Transgenic Models of Retinitis Pigmentosa

by Tam, Beatrice M., Noorwez, Syed M., Kaushal, Shalesh, Kono, Masahiro, Moritz, Orson L.
Published 2014

The Role of Subunit Assembly in Peripherin-2 Targeting to Rod Photoreceptor Disk Membranes and Retinitis Pigmentosa

by Loewen, Christopher J.R., Moritz, Orson L., Tam, Beatrice M., Papermaster, David S., Molday, Robert S.
Published 2003

Mutant rab8 Impairs Docking and Fusion of Rhodopsin-bearing Post-Golgi Membranes and Causes Cell Death of Transgenic Xenopus Rods

by Moritz, Orson L., Tam, Beatrice M., Hurd, Larry L., Peränen, Johan, Deretic, Dusanka, Papermaster, David S.
Published 2001

In Situ Visualization of Protein Interactions in Sensory Neurons: Glutamic Acid-Rich Proteins (GARPs) Play Differential Roles for Photoreceptor Outer Segment Scaffolding

by Ritter, Linda M., Khattree, Nidhi, Tam, Beatrice, Moritz, Orson L., Schmitz, Frank, Goldberg, Andrew F. X.
Published 2011

Mutant ELOVL4 That Causes Autosomal Dominant Stargardt-3 Macular Dystrophy Is Misrouted to Rod Outer Segment Disks

by Agbaga, Martin-Paul, Tam, Beatrice M., Wong, Jenny S., Yang, Lee Ling, Anderson, Robert E., Moritz, Orson L.
Published 2014

Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9

by Feehan, Joanna M., Chiu, Colette N., Stanar, Paloma, Tam, Beatrice M., Ahmed, Sheikh N., Moritz, Orson L.
Published in Sci Rep (2017)

Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function

by Jiang, Li, Tam, Beatrice M., Ying, Guoxing, Wu, Sen, Hauswirth, William W., Frederick, Jeanne M., Moritz, Orson L., Baehr, Wolfgang
Published in FASEB J (2015)

Uncoupling of Photoreceptor Peripherin/rds Fusogenic Activity from Biosynthesis, Subunit Assembly, and Targeting: A POTENTIAL MECHANISM FOR PATHOGENIC EFFECTS

by Ritter, Linda M., Khattree, Nidhi, Chen, Shu-Chu, Goldberg, Andrew F. X., Boesze-Battaglia, Kathleen, Tam, Beatrice M., Moritz, Orson L.
Published 2004

CRX controls retinal expression of the X-linked juvenile retinoschisis (RS1) gene

by Langmann, Thomas, Lai, Christine C. L., Weigelt, Karin, Tam, Beatrice M., Warneke-Wittstock, Regina, Moritz, Orson L., Weber, Bernhard H. F.
Published 2008

Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4

by Mazelova, Jana, Astuto-Gribble, Lisa, Inoue, Hiroki, Tam, Beatrice M, Schonteich, Eric, Prekeris, Rytis, Moritz, Orson L, Randazzo, Paul A, Deretic, Dusanka
Published 2009

Dysmorphic Photoreceptors in a P23H Mutant Rhodopsin Model of Retinitis Pigmentosa Are Metabolically Active and Capable of Regenerating to Reverse Retinal Degeneration

by Lee, Damian C., Vazquez-Chona, Felix R., Ferrell, W. Drew, Tam, Beatrice M., Jones, Bryan W., Marc, Robert E., Moritz, Orson L.
Published 2012

Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa

by Vent-Schmidt, Ruanne Y.J., Wen, Runxia H., Zong, Zusheng, Chiu, Colette N., Tam, Beatrice M., May, Christopher G., Moritz, Orson L.
Published in J Neurosci (2017)