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Mutant rab8 Impairs Docking and Fusion of Rhodopsin-bearing Post-Golgi Membranes and Causes Cell Death of Transgenic Xenopus Rods

Rab8 is a GTPase involved in membrane trafficking. In photoreceptor cells, rab8 is proposed to participate in the late stages of delivery of rhodopsin-containing post-Golgi membranes to the plasma membrane near the base of the connecting cilium. To test the function of rab8 in vivo, we generated tra...

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Detalhes bibliográficos
Main Authors: Moritz, Orson L., Tam, Beatrice M., Hurd, Larry L., Peränen, Johan, Deretic, Dusanka, Papermaster, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58598/
https://ncbi.nlm.nih.gov/pubmed/11514620
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