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Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4

Dysfunctions of primary cilia and cilia-derived sensory organelles underlie a multitude of human disorders, including retinal degeneration, yet membrane targeting to the cilium remains poorly understood. Here, we show that the newly identified ciliary targeting VxPx motif present in rhodopsin binds...

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Detalhes bibliográficos
Main Authors: Mazelova, Jana, Astuto-Gribble, Lisa, Inoue, Hiroki, Tam, Beatrice M, Schonteich, Eric, Prekeris, Rytis, Moritz, Orson L, Randazzo, Paul A, Deretic, Dusanka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637330/
https://ncbi.nlm.nih.gov/pubmed/19153612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.267
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