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The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking

The small GTPase Arf4 and the Arf GTPase-activating protein (GAP) ASAP1 cooperatively sequester sensory receptor cargo into transport carriers targeted to primary cilia, but the input that drives Arf4 activation in this process remains unknown. Here, we show, by using frog retinas and recombinant hu...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Wang, Jing, Fresquez, Theresa, Kandachar, Vasundhara, Deretic, Dusanka
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769590/
https://ncbi.nlm.nih.gov/pubmed/29025970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205492
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