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The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11–Rab8-mediated ciliary receptor targeting

Dysfunctional trafficking to primary cilia is a frequent cause of human diseases known as ciliopathies, yet molecular mechanisms for specific targeting of sensory receptors to cilia are largely unknown. Here, we show that the targeting of ciliary cargo, represented by rhodopsin, is mediated by a spe...

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Detalhes bibliográficos
Main Authors: Wang, Jing, Morita, Yoshiko, Mazelova, Jana, Deretic, Dusanka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474927/
https://ncbi.nlm.nih.gov/pubmed/22983554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.253
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