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The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11–Rab8-mediated ciliary receptor targeting

Dysfunctional trafficking to primary cilia is a frequent cause of human diseases known as ciliopathies, yet molecular mechanisms for specific targeting of sensory receptors to cilia are largely unknown. Here, we show that the targeting of ciliary cargo, represented by rhodopsin, is mediated by a spe...

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Bibliographic Details
Main Authors: Wang, Jing, Morita, Yoshiko, Mazelova, Jana, Deretic, Dusanka
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474927/
https://ncbi.nlm.nih.gov/pubmed/22983554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.253
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