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The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11–Rab8-mediated ciliary receptor targeting

Dysfunctional trafficking to primary cilia is a frequent cause of human diseases known as ciliopathies, yet molecular mechanisms for specific targeting of sensory receptors to cilia are largely unknown. Here, we show that the targeting of ciliary cargo, represented by rhodopsin, is mediated by a spe...

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書目詳細資料
Main Authors: Wang, Jing, Morita, Yoshiko, Mazelova, Jana, Deretic, Dusanka
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474927/
https://ncbi.nlm.nih.gov/pubmed/22983554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.253
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