When genetic burden reaches threshold

di Walsh, Roddy, Tadros, Rafik, Bezzina, Connie R
Pubblicato in Eur Heart J (2020)

Quinidine effective for the management of ventricular and atrial arrhythmias associated with Brugada syndrome

di Halperin, Laura, Mellor, Greg, Talajic, Mario, Krahn, Andrew, Tadros, Rafik, Laksman, Zachary
Pubblicato in HeartRhythm Case Rep (2018)

Beyond the “one gene-one disease” paradigm: complex genetics and pleiotropy in inheritable cardiac disorders

di Cerrone, Marina, Remme, Carol Ann, Tadros, Rafik, Bezzina, Connie R., Delmar, Mario
Pubblicato in Circulation (2019)

Guidance on Minimizing Risk of Drug-Induced Ventricular Arrhythmia During Treatment of COVID-19: A Statement from the Canadian Heart Rhythm Society

di Sapp, John L., Alqarawi, Wael, MacIntyre, Ciorsti J., Tadros, Rafik, Steinberg, Christian, Roberts, Jason D., Laksman, Zachary, Healey, Jeff S., Krahn, Andrew D.
Pubblicato in Can J Cardiol (2020)

Evaluating Polygenic Risk Scores in “Lone” Atrial Fibrillation

di Lazarte, Julieta, Dron, Jacqueline S., McIntyre, Adam D., Skanes, Allan C., Gula, Lorne J., Tang, Anthony S., Tadros, Rafik, Laksman, Zachary W., Hegele, Robert A., Roberts, Jason D.
Pubblicato in CJC Open (2021)

Exome sequencing identifies primary carnitine deficiency in a family with cardiomyopathy and sudden death

di Lahrouchi, Najim, Lodder, Elisabeth M, Mansouri, Maria, Tadros, Rafik, Zniber, Layla, Adadi, Najlae, Clur, Sally-Ann B, van Spaendonck-Zwarts, Karin Y, Postma, Alex V, Sefiani, Abdelaziz, Ratbi, Ilham, Bezzina, Connie R
Pubblicato in Eur J Hum Genet (2017)

Associations of schizophrenia with arrhythmic disorders and electrocardiogram traits: a genetic exploration of population samples

di Treur, Jorien L, Thijssen, Anaïs B, Smit, Dirk JA, Tadros, Rafik, Veeneman, Rada R, Denys, Damiaan, Vermeulen, Jentien M, Barc, Julien, Bergstedt, Jacob, Pasman, Joëlle A, Bezzina, Connie R, Verweij, Karin J H
Pubblicato in Br J Psychiatry (2024)

Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores

di Tadros, Rafik, Tan, Hanno L, el Mathari, Sulayman, Kors, Jan A, Postema, Pieter G, Lahrouchi, Najim, Beekman, Leander, Radivojkov-Blagojevic, Milena, Amin, Ahmad S, Meitinger, Thomas, Tanck, Michael W, Wilde, Arthur A, Bezzina, Connie R
Pubblicato in Eur Heart J (2019)

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity

di Harper, Andrew R., Goel, Anuj, Grace, Christopher, Thomson, Kate L., Petersen, Steffen E., Xu, Xiao, Waring, Adam, Ormondroyd, Elizabeth, Kramer, Christopher M., Ho, Carolyn Y., Neubauer, Stefan, Tadros, Rafik, Ware, James S., Bezzina, Connie R., Farrall, Martin, Watkins, Hugh
Pubblicato in Nat Genet (2021)

The Hearts in Rhythm Organization: A Canadian National Cardiogenetics Network

di Davies, Brianna, Roberts, Jason D., Tadros, Rafik, Green, Martin S., Healey, Jeffrey S., Simpson, Christopher S., Sanatani, Shubhayan, Steinberg, Christian, MacIntyre, Ciorsti, Angaran, Paul, Duff, Henry, Hamilton, Robert, Arbour, Laura, Leather, Richard, Seifer, Colette, Fournier, Anne, Atallah, Joseph, Kimber, Shane, Makanjee, Bhavanesh, Alqarawi, Wael, Cadrin-Tourigny, Julia, Joza, Jacqueline, McKinney, Jimmy, Clarke, Stephanie, Laksman, Zachary W.M., Gibbs, Karen, Vuksanovic, Vuk, Gardner, Martin, Talajic, Mario, Krahn, Andrew D.
Pubblicato in CJC Open (2020)

TECRL, a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT

di Devalla, Harsha D, Gélinas, Roselle, Aburawi, Elhadi H, Beqqali, Abdelaziz, Goyette, Philippe, Freund, Christian, Chaix, Marie‐A, Tadros, Rafik, Jiang, Hui, Le Béchec, Antony, Monshouwer‐Kloots, Jantine J, Zwetsloot, Tom, Kosmidis, Georgios, Latour, Frédéric, Alikashani, Azadeh, Hoekstra, Maaike, Schlaepfer, Jurg, Mummery, Christine L, Stevenson, Brian, Kutalik, Zoltan, de Vries, Antoine AF, Rivard, Léna, Wilde, Arthur AM, Talajic, Mario, Verkerk, Arie O, Al‐Gazali, Lihadh, Rioux, John D, Bhuiyan, Zahurul A, Passier, Robert
Pubblicato in EMBO Mol Med (2016)

Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome

di Lahrouchi, Najim, Raju, Hariharan, Lodder, Elisabeth M., Papatheodorou, Efstathios, Ware, James S., Papadakis, Michael, Tadros, Rafik, Cole, Della, Skinner, Jonathan R., Crawford, Jackie, Love, Donald R., Pua, Chee J., Soh, Bee Y., Bhalshankar, Jaydutt D., Govind, Risha, Tfelt-Hansen, Jacob, Winkel, Bo G., van der Werf, Christian, Wijeyeratne, Yanushi D., Mellor, Greg, Till, Jan, Cohen, Marta C., Tome-Esteban, Maria, Sharma, Sanjay, Wilde, Arthur A.M., Cook, Stuart A., Bezzina, Connie R., Sheppard, Mary N., Behr, Elijah R.
Pubblicato in J Am Coll Cardiol (2017)

The yield of postmortem genetic testing in sudden death cases with structural findings at autopsy

di Lahrouchi, Najim, Raju, Hariharan, Lodder, Elisabeth M., Papatheodorou, Stathis, Miles, Chris, Ware, James S., Papadakis, Michael, Tadros, Rafik, Cole, Della, Skinner, Jonathan R., Crawford, Jackie, Love, Donald R., Pua, Chee J., Soh, Bee Y., Bhalshankar, Jaydutt D., Govind, Risha, Tfelt-Hansen, Jacob, Winkel, Bo G., van der Werf, Christian, Wijeyeratne, Yanushi D., Mellor, Greg, Till, Janice, Cohen, Marta, Tome-Esteban, Maria, Sharma, Sanjay, Wilde, Arthur A. M., Cook, Stuart A., Sheppard, Mary N., Bezzina, Connie R., Behr, Elijah R.
Pubblicato in Eur J Hum Genet (2019)

SCN5A Mutation Type and a Genetic Risk Score Associate Variably With Brugada Syndrome Phenotype in SCN5A Families

di Wijeyeratne, Yanushi D., Tanck, Michael W., Mizusawa, Yuka, Batchvarov, Velislav, Barc, Julien, Crotti, Lia, Bos, J. Martijn, Tester, David J., Muir, Alison, Veltmann, Christian, Ohno, Seiko, Page, Stephen P., Galvin, Joseph, Tadros, Rafik, Muggenthaler, Martina, Raju, Hariharan, Denjoy, Isabelle, Schott, Jean-Jacques, Gourraud, Jean-Baptiste, Skoric-Milosavljevic, Doris, Nannenberg, Eline A., Redon, Richard, Papadakis, Michael, Kyndt, Florence, Dagradi, Federica, Castelletti, Silvia, Torchio, Margherita, Meitinger, Thomas, Lichtner, Peter, Ishikawa, Taisuke, Wilde, Arthur A.M., Takahashi, Kazuhiro, Sharma, Sanjay, Roden, Dan M., Borggrefe, Martin M., McKeown, Pascal P., Shimizu, Wataru, Horie, Minoru, Makita, Naomasa, Aiba, Takeshi, Ackerman, Michael J., Schwartz, Peter J., Probst, Vincent, Bezzina, Connie R., Behr, Elijah R.
Pubblicato in Circ Genom Precis Med (2020)

Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Collaboration

di Cadrin-Tourigny, Julia, Bosman, Laurens P., Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Lie, Øyvind H., Saguner, Ardan M., Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, van den Berg, Maarten P., Asselbergs, Folkert W., Wilde, Arthur A.M., Krahn, Andrew D., Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L., Kamel, Ihab R., Crosson, Jane E., Judge, Daniel P., Yap, Sing-Chien, Van der Heijden, Jeroen F., Tandri, Harikrishna, Jongbloed, Jan D.H., van Tintelen, J. Peter, Platonov, Pyotr G., Duru, Firat, Haugaa, Kristina H., Khairy, Paul, Hauer, Richard N.W., Calkins, Hugh, te Riele, Anneline S.J.M., James, Cynthia A.
Pubblicato in Circ Arrhythm Electrophysiol (2020)

Retracted and Republished: A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy

di Cadrin-Tourigny, Julia, Bosman, Laurens P, Nozza, Anna, Wang, Weijia, Tadros, Rafik, Bhonsale, Aditya, Bourfiss, Mimount, Fortier, Annik, Lie, Øyvind H, Saguner, Ardan M, Svensson, Anneli, Andorin, Antoine, Tichnell, Crystal, Murray, Brittney, Zeppenfeld, Katja, van den Berg, Maarten P, Asselbergs, Folkert W, Wilde, Arthur A M, Krahn, Andrew D, Talajic, Mario, Rivard, Lena, Chelko, Stephen, Zimmerman, Stefan L, Kamel, Ihab R, Crosson, Jane E, Judge, Daniel P, Yap, Sing-Chien, van der Heijden, Jeroen F, Tandri, Harikrishna, Jongbloed, Jan D H, Guertin, Marie-Claude, van Tintelen, J Peter, Platonov, Pyotr G, Duru, Firat, Haugaa, Kristina H, Khairy, Paul, Hauer, Richard N W, Calkins, Hugh, te Riele, Anneline S J M, James, Cynthia A
Pubblicato in Eur Heart J (2019)

An International Multi-Center Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition

di Roberts, Jason D., Asaki, S. Yukiko, Mazzanti, Andrea, Bos, J. Martijn, Tuleta, Izabela, Muir, Alison R., Crotti, Lia, Krahn, Andrew D., Kutyifa, Valentina, Shoemaker, M. Benjamin, Johnsrude, Christopher L., Aiba, Takeshi, Marcondes, Luciana, Baban, Anwar, Udupa, Sharmila, Dechert, Brynn, Fischbach, Peter, Knight, Linda M., Vittinghoff, Eric, Kukavica, Deni, Stallmeyer, Birgit, Giudicessi, John R., Spazzolini, Carla, Shimamoto, Keiko, Tadros, Rafik, Cadrin-Tourigny, Julia, Duff, Henry J., Simpson, Christopher S., Roston, Thomas M., Wijeyeratne, Yanushi D., Hajjaji, Imane El, Yousif, Maisoon D., Gula, Lorne J., Leong-Sit, Peter, Chavali, Nikhil, Landstrom, Andrew P., Marcus, Gregory M., Dittmann, Sven, Wilde, Arthur A. M., Behr, Elijah R., Tfelt-Hansen, Jacob, Scheinman, Melvin M., Perez, Marco V., Kaski, Juan Pablo, Gow, Robert M., Drago, Fabrizio, Aziz, Peter F., Abrams, Dominic J., Gollob, Michael H., Skinner, Jonathan R., Shimizu, Wataru, Kaufman, Elizabeth S., Roden, Dan M., Zareba, Wojciech, Schwartz, Peter J., Schulze-Bahr, Eric, Etheridge, Susan P., Priori, Silvia G., Ackerman, Michael J.
Pubblicato in Circulation (2020)

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

di Tadros, Rafik, Francis, Catherine, Xu, Xiao, Vermeer, Alexa M. C., Harper, Andrew R., Huurman, Roy, Bisabu, Ken Kelu, Walsh, Roddy, Hoorntje, Edgar T., te Rijdt, Wouter P., Buchan, Rachel J., van Velzen, Hannah G., van Slegtenhorst, Marjon A., Vermeulen, Jentien M., Offerhaus, Joost Allard, Bai, Wenjia, de Marvao, Antonio, Lahrouchi, Najim, Beekman, Leander, Karper, Jacco C., Veldink, Jan H., Kayvanpour, Elham, Pantazis, Antonis, Baksi, A. John, Whiffin, Nicola, Mazzarotto, Francesco, Sloane, Geraldine, Suzuki, Hideaki, Schneider-Luftman, Deborah, Elliott, Paul, Richard, Pascale, Ader, Flavie, Villard, Eric, Lichtner, Peter, Meitinger, Thomas, Tanck, Michael W. T., van Tintelen, J. Peter, Thain, Andrew, McCarty, David, Hegele, Robert A., Roberts, Jason D., Amyot, Julie, Dubé, Marie-Pierre, Cadrin-Tourigny, Julia, Giraldeau, Geneviève, L’Allier, Philippe L., Garceau, Patrick, Tardif, Jean-Claude, Boekholdt, S. Matthijs, Lumbers, R. Thomas, Asselbergs, Folkert W., Barton, Paul J. R., Cook, Stuart A., Prasad, Sanjay K., O’Regan, Declan P., van der Velden, Jolanda, Verweij, Karin J. H., Talajic, Mario, Lettre, Guillaume, Pinto, Yigal M., Meder, Benjamin, Charron, Philippe, de Boer, Rudolf A., Christiaans, Imke, Michels, Michelle, Wilde, Arthur A. M., Watkins, Hugh, Matthews, Paul M., Ware, James S., Bezzina, Connie R.
Pubblicato in Nat Genet (2021)

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

di Lahrouchi, Najim, Tadros, Rafik, Crotti, Lia, Mizusawa, Yuka, Postema, Pieter G., Beekman, Leander, Walsh, Roddy, Hasegawa, Kanae, Barc, Julien, Ernsting, Marko, Turkowski, Kari L., Mazzanti, Andrea, Beckmann, Britt M., Shimamoto, Keiko, Diamant, Ulla-Britt, Wijeyeratne, Yanushi D., Kucho, Yu, Robyns, Tomas, Ishikawa, Taisuke, Arbelo, Elena, Christiansen, Michael, Winbo, Annika, Jabbari, Reza, Lubitz, Steven A., Steinfurt, Johannes, Rudic, Boris, Loeys, Bart, Shoemaker, M. Ben, Weeke, Peter E., Pfeiffer, Ryan, Davies, Brianna, Andorin, Antoine, Hofman, Nynke, Dagradi, Federica, Pedrazzini, Matteo, Tester, David J., Bos, J. Martijn, Sarquella-Brugada, Georgia, Campuzano, Óscar, Platonov, Pyotr G., Stallmeyer, Birgit, Zumhagen, Sven, Nannenberg, Eline A., Veldink, Jan H., van den Berg, Leonard H., Al-Chalabi, Ammar, Shaw, Christopher E., Shaw, Pamela J., Morrison, Karen E., Andersen, Peter M., Müller-Nurasyid, Martina, Cusi, Daniele, Barlassina, Cristina, Galan, Pilar, Lathrop, Mark, Munter, Markus, Werge, Thomas, Ribasés, Marta, Aung, Tin, Khor, Chiea C., Ozaki, Mineo, Lichtner, Peter, Meitinger, Thomas, van Tintelen, J. Peter, Hoedemaekers, Yvonne, Denjoy, Isabelle, Leenhardt, Antoine, Napolitano, Carlo, Shimizu, Wataru, Schott, Jean-Jacques, Gourraud, Jean-Baptiste, Makiyama, Takeru, Ohno, Seiko, Itoh, Hideki, Krahn, Andrew D., Antzelevitch, Charles, Roden, Dan M., Saenen, Johan, Borggrefe, Martin, Odening, Katja E., Ellinor, Patrick T., Tfelt-Hansen, Jacob, Skinner, Jonathan R., van den Berg, Maarten P., Olesen, Morten Salling, Brugada, Josep, Brugada, Ramón, Makita, Naomasa, Breckpot, Jeroen, Yoshinaga, Masao, Behr, Elijah R., Rydberg, Annika, Aiba, Takeshi, Kääb, Stefan, Priori, Silvia G., Guicheney, Pascale, Tan, Hanno L., Newton-Cheh, Christopher, Ackerman, Michael J., Schwartz, Peter J., Schulze-Bahr, Eric, Probst, Vincent, Horie, Minoru, Wilde, Arthur A., Tanck, Michael W.T., Bezzina, Connie R.
Pubblicato in Circulation (2020)

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

di Walsh, Roddy, Lahrouchi, Najim, Tadros, Rafik, Kyndt, Florence, Glinge, Charlotte, Postema, Pieter G., Amin, Ahmad S., Nannenberg, Eline A., Ware, James S., Whiffin, Nicola, Mazzarotto, Francesco, Škorić-Milosavljević, Doris, Krijger, Christian, Arbelo, Elena, Babuty, Dominique, Barajas-Martinez, Hector, Beckmann, Britt M., Bézieau, Stéphane, Bos, J. Martijn, Breckpot, Jeroen, Campuzano, Oscar, Castelletti, Silvia, Celen, Candan, Clauss, Sebastian, Corveleyn, Anniek, Crotti, Lia, Dagradi, Federica, de Asmundis, Carlo, Denjoy, Isabelle, Dittmann, Sven, Ellinor, Patrick T., Ortuño, Cristina Gil, Giustetto, Carla, Gourraud, Jean-Baptiste, Hazeki, Daisuke, Horie, Minoru, Ishikawa, Taisuke, Itoh, Hideki, Kaneko, Yoshiaki, Kanters, Jørgen K., Kimoto, Hiroki, Kotta, Maria-Christina, Krapels, Ingrid P. C., Kurabayashi, Masahiko, Lazarte, Julieta, Leenhardt, Antoine, Loeys, Bart L., Lundin, Catarina, Makiyama, Takeru, Mansourati, Jacques, Martins, Raphaël P., Mazzanti, Andrea, Mörner, Stellan, Napolitano, Carlo, Ohkubo, Kimie, Papadakis, Michael, Rudic, Boris, Molina, Maria Sabater, Sacher, Frédéric, Sahin, Hatice, Sarquella-Brugada, Georgia, Sebastiano, Regina, Sharma, Sanjay, Sheppard, Mary N., Shimamoto, Keiko, Shoemaker, M. Benjamin, Stallmeyer, Birgit, Steinfurt, Johannes, Tanaka, Yuji, Tester, David J., Usuda, Keisuke, van der Zwaag, Paul A., Van Dooren, Sonia, Van Laer, Lut, Winbo, Annika, Winkel, Bo G., Yamagata, Kenichiro, Zumhagen, Sven, Volders, Paul G. A., Lubitz, Steven A., Antzelevitch, Charles, Platonov, Pyotr G., Odening, Katja E., Roden, Dan M., Roberts, Jason D., Skinner, Jonathan R., Tfelt-Hansen, Jacob, van den Berg, Maarten P., Olesen, Morten S., Lambiase, Pier D., Borggrefe, Martin, Hayashi, Kenshi, Rydberg, Annika, Nakajima, Tadashi, Yoshinaga, Masao, Saenen, Johan B., Kääb, Stefan, Brugada, Pedro, Robyns, Tomas, Giachino, Daniela F., Ackerman, Michael J., Brugada, Ramon, Brugada, Josep, Gimeno, Juan R., Hasdemir, Can, Guicheney, Pascale, Priori, Silvia G., Schulze-Bahr, Eric, Makita, Naomasa, Schwartz, Peter J., Shimizu, Wataru, Aiba, Takeshi, Schott, Jean-Jacques, Redon, Richard, Ohno, Seiko, Probst, Vincent, Behr, Elijah R., Barc, Julien, Bezzina, Connie R.
Pubblicato in Genet Med (2020)