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Beyond the “one gene-one disease” paradigm: complex genetics and pleiotropy in inheritable cardiac disorders
Inheritable cardiac disorders often associate with increased risk of sudden death in the young, as well as with structural damage to the myocardium. Early linkage analysis studies in Mendelian forms of these diseases, such as hypertrophic cardiomyopathy and long QT syndrome, uncovered large-effect g...
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| Publicado no: | Circulation |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697136/ https://ncbi.nlm.nih.gov/pubmed/31403841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.035954 |
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