The role of genomics and genetics in pulmonary arterial hypertension

von Swietlik, Emilia M., Gräf, Stefan, Morrell, Nicholas W.
Veröffentlicht in Glob Cardiol Sci Pract (2020)

‘There and Back Again’—Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension

von Swietlik, Emilia M., Prapa, Matina, Martin, Jennifer M., Pandya, Divya, Auckland, Kathryn, Morrell, Nicholas W., Gräf, Stefan
Veröffentlicht in Genes (Basel) (2020)

Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension

von Ulrich, Anna, Otero-Núñez, Pablo, Wharton, John, Swietlik, Emilia M., Gräf, Stefan, Morrell, Nicholas W., Wang, Dennis, Lawrie, Allan, Wilkins, Martin R., Prokopenko, Inga, Rhodes, Christopher J.
Veröffentlicht in Genes (Basel) (2020)

Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension

von Swietlik, Emilia M., Ghataorhe, Pavandeep, Zalewska, Kasia I., Wharton, John, Howard, Luke S., Taboada, Dolores, Cannon, John E., Morrell, Nicholas W., Wilkins, Martin R., Toshner, Mark, Pepke-Zaba, Joanna, Rhodes, Christopher J.
Veröffentlicht in Eur Respir J (2021)

Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension

von Ulrich, Anna, Wharton, John, Thayer, Timothy E., Swietlik, Emilia M., Assad, Tufik R., Desai, Ankit A., Gräf, Stefan, Harbaum, Lars, Humbert, Marc, Morrell, Nicholas W., Nichols, William C., Soubrier, Florent, Southgate, Laura, Trégouët, David-Alexandre, Trembath, Richard C., Brittain, Evan L., Wilkins, Martin R., Prokopenko, Inga, Rhodes, Christopher J.
Veröffentlicht in Eur Respir J (2020)

Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

von Zhu, Na, Swietlik, Emilia M., Welch, Carrie L., Pauciulo, Michael W., Hagen, Jacob J., Zhou, Xueya, Guo, Yicheng, Karten, Johannes, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Martin, Jennifer M., Treacy, Carmen M., Rosenzweig, Erika B., Krishnan, Usha, Coleman, Anna W., Gonzaga-Juaregui, Claudia, Lawrie, Allan, Trembath, Richard C., Wilkins, Martin R., Morrell, Nicholas W., Shen, Yufeng, Gräf, Stefan, Nichols, William C., Chung, Wendy K.
Veröffentlicht in Genome Med (2021)

Correction to: Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

von Zhu, Na, Swietlik, Emilia M., Welch, Carrie L., Pauciulo, Michael W., Hagen, Jacob J., Zhou, Xueya, Guo, Yicheng, Karten, Johannes, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Martin, Jennifer M., Treacy, Carmen M., Rosenzweig, Erika B., Krishnan, Usha, Coleman, Anna W., Gonzaga-Jauregui, Claudia, Lawrie, Allan, Trembath, Richard C., Wilkins, Martin R., Morrell, Nicholas W., Shen, Yufeng, Gräf, Stefan, Nichols, William C., Chung, Wendy K.
Veröffentlicht in Genome Med (2021)

Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome

von Rhodes, Christopher J., Otero-Núñez, Pablo, Wharton, John, Swietlik, Emilia M., Kariotis, Sokratis, Harbaum, Lars, Dunning, Mark J., Elinoff, Jason M., Errington, Niamh, Thompson, A. A. Roger, Iremonger, James, Coghlan, J. Gerry, Corris, Paul A., Howard, Luke S., Kiely, David G., Church, Colin, Pepke-Zaba, Joanna, Toshner, Mark, Wort, Stephen J., Desai, Ankit A., Humbert, Marc, Nichols, William C., Southgate, Laura, Trégouët, David-Alexandre, Trembath, Richard C., Prokopenko, Inga, Gräf, Stefan, Morrell, Nicholas W., Wang, Dennis, Lawrie, Allan
Veröffentlicht in Am J Respir Crit Care Med (2020)

Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension

von Jones, Rowena J., De Bie, Eckart M. D. D., Groves, Emily, Zalewska, Kasia I., Swietlik, Emilia M., Treacy, Carmen M., Martin, Jennifer M., Polwarth, Gary, Li, Wei, Guo, Jingxu, Baxendale, Helen E., Coleman, Stephen, Savinykh, Natalia, Coghlan, J. Gerry, Corris, Paul A., Howard, Luke S., Johnson, Martin K., Church, Colin, Kiely, David G., Lawrie, Allan, Lordan, James L., Mackenzie Ross, Robert V., Pepke Zaba, Joanna, Wilkins, Martin R., Wort, S. John, Fiorillo, Edoardo, Orrù, Valeria, Cucca, Francesco, Rhodes, Christopher J., Gräf, Stefan, Morrell, Nicholas W., McKinney, Eoin F., Wallace, Chris, Toshner, Mark
Veröffentlicht in Am J Respir Crit Care Med (2022)

Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension

von Hodgson, Joshua, Swietlik, Emilia M., Salmon, Richard M., Hadinnapola, Charaka, Nikolic, Ivana, Wharton, John, Guo, Jingxu, Liley, James, Haimel, Matthias, Bleda, Marta, Southgate, Laura, Machado, Rajiv D., Martin, Jennifer M., Treacy, Carmen M., Yates, Katherine, Daugherty, Louise C., Shamardina, Olga, Whitehorn, Deborah, Holden, Simon, Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A., Danesino, Cesare, Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J. Simon R., Girerd, Barbara, Houweling, Arjan C., Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, Lawrie, Allan, MacKenzie Ross, Robert V., Moledina, Shahin, Montani, David, Olschewski, Andrea, Olschewski, Horst, Ouwehand, Willem H., Peacock, Andrew J., Pepke-Zaba, Joanna, Prokopenko, Inga, Rhodes, Christopher J., Scelsi, Laura, Seeger, Werner, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark R., Trembath, Richard C., Noordegraaf, Anton Vonk, Wort, Stephen J., Wilkins, Martin R., Yu, Paul B., Li, Wei, Gräf, Stefan, Upton, Paul D., Morrell, Nicholas W.
Veröffentlicht in Am J Respir Crit Care Med (2019)

Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension

von Swietlik, Emilia M., Greene, Daniel, Zhu, Na, Megy, Karyn, Cogliano, Marcella, Rajaram, Smitha, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Welch, Carrie C.L., Pauciulo, Michael W., Southgate, Laura, Martin, Jennifer M., Treacy, Carmen M., Penkett, Christopher J., Stephens, Jonathan C., Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Coleman, Anna W., Condliffe, Robin, Eichstaedt, Christina A., Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Girerd, Barbara, Grünig, Ekkehard, Holden, Simon, Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, Lordan, Jim, Machado, Rajiv D., MacKenzie Ross, Robert V., McCabe, Colm, Moledina, Shahin, Montani, David, Olschewski, Horst, Pepke-Zaba, Joanna, Price, Laura, Rhodes, Christopher J., Seeger, Werner, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark R., Vonk Noordegraaf, Anton, Wharton, John, Wild, James M., Wort, Stephen John, Lawrie, Allan, Wilkins, Martin R., Trembath, Richard C., Shen, Yufeng, Chung, Wendy K., Swift, Andrew J., Nichols, William C., Morrell, Nicholas W., Gräf, Stefan
Veröffentlicht in Circ Genom Precis Med (2020)

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

von Gräf, Stefan, Haimel, Matthias, Bleda, Marta, Hadinnapola, Charaka, Southgate, Laura, Li, Wei, Hodgson, Joshua, Liu, Bin, Salmon, Richard M., Southwood, Mark, Machado, Rajiv D., Martin, Jennifer M., Treacy, Carmen M., Yates, Katherine, Daugherty, Louise C., Shamardina, Olga, Whitehorn, Deborah, Holden, Simon, Aldred, Micheala, Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A., Danesino, Cesare, Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J. Simon R., Girerd, Barbara, Houweling, Arjan C., Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, MacKenzie Ross, Robert V., Moledina, Shahin, Montani, David, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Peacock, Andrew J., Pepke-Zaba, Joanna, Prokopenko, Inga, Rhodes, Christopher J., Scelsi, Laura, Seeger, Werner, Soubrier, Florent, Stein, Dan F., Suntharalingam, Jay, Swietlik, Emilia M., Toshner, Mark R., van Heel, David A., Vonk Noordegraaf, Anton, Waisfisz, Quinten, Wharton, John, Wort, Stephen J., Ouwehand, Willem H., Soranzo, Nicole, Lawrie, Allan, Upton, Paul D., Wilkins, Martin R., Trembath, Richard C., Morrell, Nicholas W.
Veröffentlicht in Nat Commun (2018)

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

von Rhodes, Christopher J, Batai, Ken, Bleda, Marta, Haimel, Matthias, Southgate, Laura, Germain, Marine, Pauciulo, Michael W, Hadinnapola, Charaka, Aman, Jurjan, Girerd, Barbara, Arora, Amit, Knight, Jo, Hanscombe, Ken B, Karnes, Jason H, Kaakinen, Marika, Gall, Henning, Ulrich, Anna, Harbaum, Lars, Cebola, Inês, Ferrer, Jorge, Lutz, Katie, Swietlik, Emilia M, Ahmad, Ferhaan, Amouyel, Philippe, Archer, Stephen L, Argula, Rahul, Austin, Eric D, Badesch, David, Bakshi, Sahil, Barnett, Christopher, Benza, Raymond, Bhatt, Nitin, Bogaard, Harm J, Burger, Charles D, Chakinala, Murali, Church, Colin, Coghlan, John G, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Debette, Stéphanie, Elliott, C Gregory, Elwing, Jean, Eyries, Melanie, Fortin, Terry, Franke, Andre, Frantz, Robert P, Frost, Adaani, Garcia, Joe G N, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Harley, John, He, Hua, Hill, Nicholas S, Hirsch, Russel, Houweling, Arjan C, Howard, Luke S, Ivy, Dunbar, Kiely, David G, Klinger, James, Kovacs, Gabor, Lahm, Tim, Laudes, Matthias, Machado, Rajiv D, MacKenzie Ross, Robert V, Marsolo, Keith, Martin, Lisa J, Moledina, Shahin, Montani, David, Nathan, Steven D, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Oudiz, Ronald J, Ouwehand, Willem H, Peacock, Andrew J, Pepke-Zaba, Joanna, Rehman, Zia, Robbins, Ivan, Roden, Dan M, Rosenzweig, Erika B, Saydain, Ghulam, Scelsi, Laura, Schilz, Robert, Seeger, Werner, Shaffer, Christian M, Simms, Robert W, Simon, Marc, Sitbon, Olivier, Suntharalingam, Jay, Tang, Haiyang, Tchourbanov, Alexander Y, Thenappan, Thenappan, Torres, Fernando, Toshner, Mark R, Treacy, Carmen M, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Walsworth, Anna K, Walter, Robert E, Wharton, John, White, R James, Wilt, Jeffrey, Wort, Stephen J, Yung, Delphine, Lawrie, Allan, Humbert, Marc, Soubrier, Florent, Trégouët, David-Alexandre, Prokopenko, Inga, Kittles, Richard, Gräf, Stefan, Nichols, William C, Trembath, Richard C, Desai, Ankit A, Morrell, Nicholas W, Wilkins, Martin R
Veröffentlicht in Lancet Respir Med (2019)