Safety, Tolerability, and Pharmacokinetics of Mevidalen (LY3154207), a Centrally Acting Dopamine D1 Receptor‐Positive Allosteric Modulator (D1PAM), in Healthy Subjects

par Wilbraham, Darren, Biglan, Kevin M., Svensson, Kjell A., Tsai, Max, Kielbasa, William
Publié dans Clin Pharmacol Drug Dev (2020)

Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats

par Johnson, Philip L, Fitz, Stephanie D, Engleman, Eric A, Svensson, Kjell A, Schkeryantz, Jeffrey M, Shekhar, Anantha
Publié dans J Psychopharmacol (2012)

Dopamine Agonist-Induced Yawning in Rats: A Dopamine D3 Receptor-Mediated Behavior

par Collins, Gregory T., Witkin, Jeffrey M., Newman, Amy H., Svensson, Kjell A., Grundt, Peter, Cao, Jianjing, Woods, James H.
Publié 2005

Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H(1) Receptor Blockade

par Fell, Matthew J., Katner, Jason S., Rasmussen, Kurt, Nikolayev, Alexander, Kuo, Ming-Shang, Nelson, David L. G., Perry, Kenneth W., Svensson, Kjell A.
Publié 2012

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

par Bradley, Sophie J., Molloy, Colin, Valuskova, Paulina, Dwomoh, Louis, Scarpa, Miriam, Rossi, Mario, Finlayson, Lisa, Svensson, Kjell A., Chernet, Eyassu, Barth, Vanessa N., Gherbi, Karolina, Sykes, David A., Wilson, Caroline A., Mistry, Rajendra, Sexton, Patrick M., Christopoulos, Arthur, Mogg, Adrian J., Rosethorne, Elizabeth M., Sakata, Shuzo, Challiss, R. A. John, Broad, Lisa M., Tobin, Andrew B.
Publié dans Nat Chem Biol (2020)

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

par Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Publié dans Pharmacol Res Perspect (2016)

An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis

par Svensson, Kjell A., Heinz, Beverly A., Schaus, John M., Beck, James P., Hao, Junliang, Krushinski, Joseph H., Reinhard, Matthew R., Cohen, Michael P., Hellman, Sarah L., Getman, Brian G., Wang, Xushan, Menezes, Michelle M., Maren, Deanna L., Falcone, Julie F., Anderson, Wesley H., Wright, Rebecca A., Morin, S. Michelle, Knopp, Kelly L., Adams, Benjamin L., Rogovoy, Borys, Okun, Ilya, Suter, Todd M., Statnick, Michael A., Gehlert, Donald R., Nelson, David L., Lucaites, Virginia L., Emkey, Renee, DeLapp, Neil W., Wiernicki, Todd R., Cramer, Jeffrey W., Yang, Charles R., Bruns, Robert F.
Publié dans J Pharmacol Exp Ther (2017)