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Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats

Rats with chronic inhibition of GABA synthesis by infusion of l-allyglycine, a glutamic acid decarboxylase inhibitor, into their dorsomedial/perifornical hypothalamus are anxious and exhibit panic-like cardio-respiratory responses to treatment with intravenous (i.v.) sodium lactate (NaLac) infusions...

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Detalhes bibliográficos
Publicado no:J Psychopharmacol
Main Authors: Johnson, Philip L, Fitz, Stephanie D, Engleman, Eric A, Svensson, Kjell A, Schkeryantz, Jeffrey M, Shekhar, Anantha
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300988/
https://ncbi.nlm.nih.gov/pubmed/22914798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112454230
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