Changes in Central Sodium and not Osmolarity or Lactate Induce Panic-Like Responses in a Model of Panic Disorder

Panic disorder is a severe anxiety disorder characterized by recurrent panic attacks that can be consistently provoked with intravenous (i.v.) infusions of hypertonic (0.5 M) sodium lactate (NaLac), yet the mechanism/CNS site by which this stimulus triggers panic attacks is unclear. Chronic inhibiti...

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Detalhes bibliográficos
Main Authors: Molosh, Andre I, Johnson, Philip L, Fitz, Stephanie D, DiMicco, Joseph A, Herman, James P, Shekhar, Anantha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855744/
https://ncbi.nlm.nih.gov/pubmed/20130534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.2
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