Expression of Apolipoprotein B in the Kidney Attenuates Renal Lipid Accumulation

par Krzystanek, Marcin, Pedersen, Tanja Xenia, Bartels, Emil Daniel, Kjæhr, Jacob, Straarup, Ellen Marie, Nielsen, Lars Bo
Publié 2010

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

par Gupta, Nidhi, Fisker, Niels, Asselin, Marie-Claude, Lindholm, Marie, Rosenbohm, Christoph, Ørum, Henrik, Elmén, Joacim, Seidah, Nabil G., Straarup, Ellen Marie
Publié 2010

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

par Worm, Jesper, Stenvang, Jan, Petri, Andreas, Frederiksen, Klaus Stensgaard, Obad, Susanna, Elmén, Joacim, Hedtjärn, Maj, Straarup, Ellen Marie, Hansen, Jens Bo, Kauppinen, Sakari
Publié 2009

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

par Straarup, Ellen Marie, Fisker, Niels, Hedtjärn, Maj, Lindholm, Marie W., Rosenbohm, Christoph, Aarup, Vibeke, Hansen, Henrik Frydenlund, Ørum, Henrik, Hansen, Jens B. Rode, Koch, Troels
Publié 2010

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

par Elmén, Joacim, Lindow, Morten, Silahtaroglu, Asli, Bak, Mads, Christensen, Mette, Lind-Thomsen, Allan, Hedtjärn, Maj, Hansen, Jens Bo, Hansen, Henrik Frydenlund, Straarup, Ellen Marie, McCullagh, Keith, Kearney, Phil, Kauppinen, Sakari
Publié 2008

Silencing of microRNA families by seed-targeting tiny LNAs

par Obad, Susanna, dos Santos, Camila O, Petri, Andreas, Heidenblad, Markus, Broom, Oliver, Ruse, Cristian, Fu, Cexiong, Lindow, Morten, Stenvang, Jan, Straarup, Ellen Marie, Hansen, Henrik Frydenlund, Koch, Troels, Pappin, Darryl, Hannon, Gregory J, Kauppinen, Sakari
Publié 2011