High Content Screening of Diverse Compound Libraries Identifies Potent Modulators of Tubulin Dynamics

Por Laraia, Luca, Stokes, Jamie, Emery, Amy, McKenzie, Grahame J., Venkitaraman, Ashok R., Spring, David R.
Publicado em 2014

A Multidimensional Diversity‐Oriented Synthesis Strategy for Structurally Diverse and Complex Macrocycles

Por Nie, Feilin, Kunciw, Dominique L., Wilcke, David, Stokes, Jamie E., Galloway, Warren R. J. D., Bartlett, Sean, Sore, Hannah F., Spring, David R.
Publicado no Angew Chem Int Ed Engl (2016)

Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck–Suzuki reaction

Por Alza, Esther, Laraia, Luca, Ibbeson, Brett M., Collins, Súil, Galloway, Warren R. J. D., Stokes, Jamie E., Venkitaraman, Ashok R., Spring, David R.
Publicado no Chem Sci (2015)

Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons

Por Bilsland, Elizabeth, Tavella, Tatyana A., Krogh, Renata, Stokes, Jamie E., Roberts, Annabelle, Ajioka, James, Spring, David R., Andricopulo, Adriano D., Costa, Fabio T. M., Oliver, Stephen G.
Publicado no BMC Biotechnol (2018)

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

Por Chattopadhyay, Anasuya, O’Connor, Cornelius J., Zhang, Fengzhi, Galvagnion, Celine, Galloway, Warren R. J. D., Tan, Yaw Sing, Stokes, Jamie E., Rahman, Taufiq, Verma, Chandra, Spring, David R., Itzhaki, Laura S.
Publicado no Sci Rep (2016)

Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase–TPX2 protein–protein interaction

Por Cole, Daniel J., Janecek, Matej, Stokes, Jamie E., Rossmann, Maxim, Faver, John C., McKenzie, Grahame J., Venkitaraman, Ashok R., Hyvönen, Marko, Spring, David R., Huggins, David J., Jorgensen, William L.
Publicado no Chem Commun (Camb) (2017)

Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2

Por Janeček, Matej, Rossmann, Maxim, Sharma, Pooja, Emery, Amy, Huggins, David J., Stockwell, Simon R., Stokes, Jamie E., Tan, Yaw S., Almeida, Estrella Guarino, Hardwick, Bryn, Narvaez, Ana J., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.
Publicado no Sci Rep (2016)