Lifespan effects of simple and complex nutraceutical combinations fed isocalorically to mice

Por Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Publicado em 2013

Dietary supplementation with Lovaza and krill oil shortens the life span of long-lived F1 mice

Por Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Publicado em 2014

Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice

Por Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Publicado no Age (Dordr) (2016)

Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

Por Cao, Shelley X., Dhahbi, Joseph M., Mote, Patricia L., Spindler, Stephen R.
Publicado em 2001

Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

Por Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Sauer, Frank
Publicado em 2012

Deep Sequencing of Serum Small RNAs Identifies Patterns of 5′ tRNA Half and YRNA Fragment Expression Associated with Breast Cancer

Por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Boffelli, Dario, Martin, David IK
Publicado no Biomark Cancer (2014)

mRNA-Seq reveals complex patterns of gene regulation and expression in the mouse skeletal muscle transcriptome associated with calorie restriction

Por Dhahbi, Joseph M., Atamna, Hani, Boffelli, Dario, Martin, David I. K., Spindler, Stephen R.
Publicado em 2012

Temporal linkage between the phenotypic and genomic responses to caloric restriction

Por Dhahbi, Joseph M., Kim, Hyon-Jeen, Mote, Patricia L., Beaver, Robert J., Spindler, Stephen R.
Publicado em 2004

Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence

Por Dhahbi, Joseph M., Atamna, Hani, Boffelli, Dario, Magis, Wendy, Spindler, Stephen R., Martin, David I. K.
Publicado em 2011

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

Por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Boffelli, Dario, Mote, Patricia, Martin, David IK
Publicado em 2013

Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice

Por Spindler, Stephen R., Mote, Patricia L., Lublin, Alex L., Flegal, James M., Dhahbi, Joseph M., Li, Rui
Publicado no J Gerontol A Biol Sci Med Sci (2015)

Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response

Por Wu, Yong, Lin, Joy C., Piluso, Landon G., Dhahbi, Joseph M., Bobadilla, Selene, Spindler, Stephen R., Liu, Xuan
Publicado em 2013

MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner

Por Dhahbi, Joseph M., Atamna, Hani, Li, Rui, Yamakawa, Amy, Guerrero, Noel, Lam, Hanh T., Mote, Patricia, Spindler, Stephen R.
Publicado no Genomics Insights (2016)

Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction

Por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Guerrero, Noel, Boffelli, Dario, Mote, Patricia, Martin, David IK
Publicado em 2013

Circulating microRNA signature of genotype‐by‐age interactions in the long‐lived Ames dwarf mouse

Por Victoria, Berta, Dhahbi, Joseph M., Nunez Lopez, Yury O., Spinel, Lina, Atamna, Hani, Spindler, Stephen R., Masternak, Michal M.
Publicado no Aging Cell (2015)

Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation

Por Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Mote, Patricia, Bodmer, Rolf, Ocorr, Karen, Williams, Renee T., Wang, Yinsheng, Ablao, Kenneth P.
Publicado em 2012

β1-Adrenergic receptor blockade extends the life span of Drosophila and long-lived mice

Por Spindler, Stephen R., Mote, Patricia L., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Flegal, James M., Jeske, Daniel R., Li, Rui, Lublin, Alex L.
Publicado em 2013

Circulating small non coding RNA signature in head and neck squamous cell carcinoma

Por Martinez, Berta Victoria, Dhahbi, Joseph M., Lopez, Yury O. Nunez, Lamperska, Katarzyna, Golusinski, Paweł, Luczewski, Lukasz, Kolenda, Tomasz, Atamna, Hani, Spindler, Stephen R., Golusinski, Wojciech, Masternak, Michal M.
Publicado no Oncotarget (2015)

Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells

Por Vuong, Linh M., Chellappa, Karthikeyani, Dhahbi, Joseph M., Deans, Jonathan R., Fang, Bin, Bolotin, Eugene, Titova, Nina V., Hoverter, Nate P., Spindler, Stephen R., Waterman, Marian L., Sladek, Frances M.
Publicado no Mol Cell Biol (2015)

Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

Por Schumacher, Björn, van der Pluijm, Ingrid, Moorhouse, Michael J., Kosteas, Theodore, Robinson, Andria Rasile, Suh, Yousin, Breit, Timo M., van Steeg, Harry, Niedernhofer, Laura J., van IJcken, Wilfred, Bartke, Andrzej, Spindler, Stephen R., Hoeijmakers, Jan H. J., van der Horst, Gijsbertus T. J., Garinis, George A.
Publicado em 2008