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Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

Protein kinase signaling cascades control most aspects of cellular function. The ATP binding domains of signaling protein kinases are the targets of most available inhibitors. These domains are highly conserved from mammals to flies. Herein we describe screening of a library of small molecule inhibi...

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Detalhes bibliográficos
Main Authors: Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Sauer, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282711/
https://ncbi.nlm.nih.gov/pubmed/22363408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029782
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