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Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence

In cell senescence, cultured cells cease proliferating and acquire aberrant gene expression patterns. MicroRNAs (miRNAs) modulate gene expression through translational repression or mRNA degradation and have been implicated in senescence. We used deep sequencing to carry out a comprehensive survey o...

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書誌詳細
主要な著者: Dhahbi, Joseph M., Atamna, Hani, Boffelli, Dario, Magis, Wendy, Spindler, Stephen R., Martin, David I. K.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102725/
https://ncbi.nlm.nih.gov/pubmed/21637828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020509
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